Suppr超能文献

来自[植物名称]根中的两种新化合物及其抗炎活性。 (你提供的原文中“from the roots of”后面缺少具体植物名称)

Two new compounds from the roots of and their anti-inflammatory activities.

作者信息

Huo Yu-Feng, Wang Huai-Li, Wei Er-Hu, Jia Pei-Sheng, Liu Hui-Qiong, Fan Xiao-Lei, Yana Kun-Li

机构信息

Department of Pediatrics, The First Affiliated Hospital of Zhengzhou University , Zhengzhou 450052 , China.

出版信息

J Asian Nat Prod Res. 2019 Nov;21(11):1083-1089. doi: 10.1080/10286020.2018.1513919. Epub 2019 Jan 6.

Abstract

Aiming to investigate the bioactive constituents with anti-inflammatory activity from the roots of , two new compounds ( and ) were isolated from the extract of the roots of the plant. Their structures were elucidated on the basis of spectral analyses (UV, IR, NMR, and MS spectroscopy), as well as experimental and calculated electronic circular dichroism (ECD) analyses. All of the isolates were tested for their anti-inflammatory properties in terms of suppressing the production of NO in lipopolysaccharide-induced BV2 cells. Compound exhibited stronger anti-inflammatory effects (77.65%) than the positive control curcumin (69.75%) at 10 M.

摘要

为了从该植物的根中研究具有抗炎活性的生物活性成分,从该植物根的提取物中分离出两种新化合物(化合物1和化合物2)。它们的结构是基于光谱分析(紫外、红外、核磁共振和质谱光谱)以及实验和计算的电子圆二色性(ECD)分析确定的。所有分离物均在抑制脂多糖诱导的BV2细胞中一氧化氮产生方面测试了其抗炎特性。在10 μM时,化合物1表现出比阳性对照姜黄素(69.75%)更强的抗炎作用(77.65%)。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验