a Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), Academic Unit of Obstetrics and Gynecology , University of Genova , Genova , Italy.
b Physiopathology of Human Reproduction Unit , Ospedale Policlinico San Martino , Genova , Italy.
Gynecol Endocrinol. 2019 Jun;35(6):485-489. doi: 10.1080/09513590.2018.1540575. Epub 2019 Jan 7.
This study aims to evaluate levels of anxiety and depression in women, correlated with infertility per se and with infertility treatments, highlighting predictors of higher levels of distress. Two validated standardized questionnaires, the Hospital Anxiety and Depression Scale (HADS) and the Fertility Quality of Life (FertiQoL), were administered to 89 women both before their first cycle of infertility treatment and again at the end of the ovarian stimulation for in vitro fertilization (IVF). Women's levels of anxiety were significantly higher before the treatment than during the treatment itself. Stratifying the women in three groups based on principal cause of infertility (male infertility, female infertility, or both male and female), we found significantly higher levels of anxiety and general distress in patients under treatment for female infertility. Higher anxiety levels in our sample before the treatment are probably an effect of not knowing what they are expected to do to solve their problem. Moreover, when the cause of infertility is exclusively female, women experience higher levels of anxiety and general distress both before and during the treatment, probably correlated to a sense of guilt. These data help the treating physician to better counsel patients and to provide a more focused psychological support.
本研究旨在评估与不孕本身及不孕治疗相关的女性焦虑和抑郁水平，重点关注导致更严重困扰的预测因素。我们对 89 名女性在接受不孕治疗的第一个周期前后分别使用两个经过验证的标准化问卷，即医院焦虑抑郁量表（HADS）和生育质量生活量表（FertiQoL）进行评估。女性在治疗前的焦虑水平明显高于治疗期间。根据不孕的主要原因（男性不孕、女性不孕或男女双方都不孕）将女性分为三组，我们发现，接受女性不孕治疗的患者焦虑和一般困扰水平显著更高。在治疗前，我们样本中的女性焦虑水平较高可能是因为她们不知道要做什么来解决问题。此外，当不孕的原因仅为女性时，女性在治疗前和治疗期间都会经历更高水平的焦虑和一般困扰，这可能与内疚感有关。这些数据有助于治疗医生更好地为患者提供咨询，并提供更有针对性的心理支持。
