Bories P, Tournade J M, Alberola B, Pappo M
Sce d'Hépato-Gastroentérologie, Hôpital Saint-Eloi, Montpellier.
Ann Gastroenterol Hepatol (Paris). 1988 Oct;24(5):227-32.
The aim of this study was to evaluate, on a wide population of outpatients, the efficacy of ranitidine 300 mg given once a day at bedtime in duodenal and gastric ulcer. Healing rates observed on 1,208 patients were 85.2% (703/825) in duodenal ulcer, 79.5% (268/337) in gastric ulcer and 71.7% (33/46) in double localization, duodenal and gastric. Analysis of predictive factors of treatment failure showed no influence of smoking on the efficacy of ranitidine neither in duodenal nor gastric ulcer.