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[A single evening dose of 300 mg ranitidine in the treatment of acute attacks of gastric and duodenal ulcers. Evaluation of 1,208 patients].

作者信息

Bories P, Tournade J M, Alberola B, Pappo M

机构信息

Sce d'Hépato-Gastroentérologie, Hôpital Saint-Eloi, Montpellier.

出版信息

Ann Gastroenterol Hepatol (Paris). 1988 Oct;24(5):227-32.

PMID:3061358
Abstract

The aim of this study was to evaluate, on a wide population of outpatients, the efficacy of ranitidine 300 mg given once a day at bedtime in duodenal and gastric ulcer. Healing rates observed on 1,208 patients were 85.2% (703/825) in duodenal ulcer, 79.5% (268/337) in gastric ulcer and 71.7% (33/46) in double localization, duodenal and gastric. Analysis of predictive factors of treatment failure showed no influence of smoking on the efficacy of ranitidine neither in duodenal nor gastric ulcer.

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