非裔美国人、西班牙裔和亚洲人黑色素瘤的临床表现。
Clinical Presentations of Melanoma in African Americans, Hispanics, and Asians.
机构信息
Department of Dermatology, Keck Medicine of USC, Los Angeles, California.
Department of Dermatology, University of Nebraska Medical Center, Omaha, Nebraska.
出版信息
Dermatol Surg. 2019 Jun;45(6):791-801. doi: 10.1097/DSS.0000000000001759.
BACKGROUND
Skin cancer has traditionally been studied in Caucasian skin. Although it does occur with increased relative frequency in Caucasians, patients with skin of color suffer from elevated morbidity and mortality when diagnosed with skin cancer.
OBJECTIVE
To detail the unique demographic, clinical, and genetic features of melanoma in patients with skin of color, including Hispanic, African American, and Asian patients.
MATERIALS AND METHODS
A PubMed search was conducted spanning dates 1947 to June 2017. A total of 246 articles were screened, from which 69 were included in this review.
RESULTS
Relative to Caucasians, melanoma has unique demographic, clinical, and genetic features in African Americans, Hispanics, and Asians that include gender and subtype predominance.
CONCLUSION
Familiarization with these unique presentations of skin cancer in skin of color is imperative to accurate identification and treatment of cutaneous malignancies in these populations and ultimately to improved disease-related outcomes.
背景
皮肤癌传统上在白种人的皮肤中进行研究。虽然在白种人中相对更频繁地发生，但患有有色人种皮肤的患者在被诊断患有皮肤癌时，发病率和死亡率更高。
目的
详细描述有色人种（包括西班牙裔、非裔美国人和亚洲人）患者黑色素瘤的独特人口统计学、临床和遗传特征。
材料和方法
对 1947 年至 2017 年 6 月的 PubMed 进行了搜索。共筛选了 246 篇文章，其中有 69 篇被纳入本综述。
结果
与白种人相比，非裔美国人、西班牙裔和亚洲人黑色素瘤具有独特的人口统计学、临床和遗传特征，包括性别和亚型优势。
结论
熟悉这些有色人种皮肤癌的独特表现对于准确识别和治疗这些人群中的皮肤恶性肿瘤至关重要，最终可改善与疾病相关的结局。
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