Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105.
Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105
J Immunol. 2019 Jan 15;202(2):392-398. doi: 10.4049/jimmunol.1801054.
The severity of the 2017-18 influenza season, combined with the low efficacy for some vaccine components, highlights the need to improve our current seasonal influenza vaccine. Thus, the National Institute of Allergy and Infectious Diseases recently announced a strategic plan to improve current influenza vaccines and eventually develop a "universal" influenza vaccine. This review will highlight the many different strategies being undertaken in pursuit of this goal and the exciting advances made by the influenza community. There is no doubt that an improved influenza vaccine is on the horizon.
2017-18 年流感季的严重程度，加上某些疫苗成分的低效率，凸显了我们需要改进当前的季节性流感疫苗。因此，美国国家过敏和传染病研究所最近宣布了一项战略计划，以改进当前的流感疫苗，并最终开发出一种“通用”流感疫苗。本文将重点介绍为实现这一目标而采取的许多不同策略，以及流感领域取得的令人兴奋的进展。毫无疑问，一种改进的流感疫苗即将面世。
