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工作单位组织变革与随后的精神药物处方:一项针对公共医疗保健员工的纵向研究。

Work-unit organisational changes and subsequent prescriptions for psychotropic medication: a longitudinal study among public healthcare employees.

机构信息

Department of Occupational and Environmental Medicine, Copenhagen University Hospital, Bispebjerg Hospital, Copenhagen, Denmark.

Department of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.

出版信息

Occup Environ Med. 2019 Mar;76(3):143-150. doi: 10.1136/oemed-2018-105442. Epub 2019 Jan 7.

Abstract

OBJECTIVES

We examined exposure to different types of organisational changes at work as risk factors for subsequent prescription for psychotropic medication among employees.

METHODS

The study population included 15 038 public healthcare employees nested within 1284 work units in the Capital Region of Denmark. Multilevel mixed-effects parametric survival models were developed to examine time to prescription for psychotropic medications (anxiolytics/hypnotics/sedatives/antidepressants) during the 12-month interval following exposure to organisational changes relative to no change from January to December 2013. Data on work-unit level organisational changes (including mergers, split-ups, relocation, change in management, employee lay-offs and budget cuts) were collected from work-unit managers (59% response).

RESULTS

Any organisational change versus no change was associated with a higher risk of psychotropic prescription (HR: 1.14, 95% CI: 1.02 to 1.26), especially change in management (HR: 1.23, 95% CI: 1.07 to 1.41). Splitting the 12-month follow-up period into two halves yielded particularly high rates of psychotropic prescription in the latter half of the follow-up, for example, any change (HR: 1.25, 95% CI: 1.11 to 1.41), change in management (HR: 1.42, 95% CI: 1.22 to 1.65), mergers (HR: 1.26, 95% CI: 1.06 to 1.50), employee lay-off (HR: 1.23, 95% CI: 1.03 to 1.46) and budget cuts (HR: 1.13, 95% CI: 1.00 to 1.41). The associations did not vary by sex.

CONCLUSIONS

Organisational changes in the workplace, especially change in management, may be associated with increased risk of psychotropic prescription among employees regardless of sex.

摘要

目的

我们研究了工作中不同类型的组织变革作为员工随后开处精神类药物处方的风险因素。

方法

研究人群包括嵌套在丹麦首都地区 1284 个工作单位内的 15038 名公共医疗保健员工。采用多水平混合效应参数生存模型,来检验 2013 年 1 月至 12 月期间接触组织变革(与无变化相比)与接触后 12 个月内开处精神类药物(抗焦虑药/催眠药/镇静剂/抗抑郁药)之间的时间关系。工作单位层面组织变革(包括合并、拆分、搬迁、管理层变更、裁员和预算削减)的数据由工作单位经理收集(59%的回应率)。

结果

与无变化相比,任何组织变革都与精神类药物处方的风险增加相关(HR:1.14,95%CI:1.02 至 1.26),尤其是管理层变更(HR:1.23,95%CI:1.07 至 1.41)。将 12 个月的随访期分为两半,在后半段随访期间,精神类药物处方的比例特别高,例如,任何变革(HR:1.25,95%CI:1.11 至 1.41)、管理层变更(HR:1.42,95%CI:1.22 至 1.65)、合并(HR:1.26,95%CI:1.06 至 1.50)、裁员(HR:1.23,95%CI:1.03 至 1.46)和预算削减(HR:1.13,95%CI:1.00 至 1.41)。这些关联在性别间无差异。

结论

工作场所的组织变革,尤其是管理层的变更,可能与员工精神类药物处方风险的增加有关,无论其性别如何。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/434d/6581106/b046c921891d/oemed-2018-105442f01.jpg

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