Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry and Chemical Engineering , Soochow Unversity , 199 Renai Street , Suzhou , Jiangsu 215123 , China.
Org Lett. 2019 Jan 18;21(2):365-368. doi: 10.1021/acs.orglett.8b03488. Epub 2019 Jan 8.
A rhodium(III)-catalyzed intermolecular C-H amination of ketoxime and iodobenzene diacetate-enabled N-N bond formation in the synthesis of indazoles has been developed. A variety of functional groups were well tolerated, providing the corresponding products in moderate to good yields. Moreover, the nitro-substituted ketoximes are well compatible in this reaction, leading to the corresponding products in moderate to good yields.
发展了铑(III)催化的酮肟和碘苯二乙酸酯的分子间 C-H 氨化反应，实现了吲唑中 N-N 键的形成。该反应具有很好的官能团耐受性，能够以中等至良好的收率得到相应的产物。此外，该反应还能很好地兼容硝基取代的酮肟，以中等至良好的收率得到相应的产物。
