Department of Sports Medicine Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Metab Syndr Relat Disord. 2019 Mar;17(2):97-101. doi: 10.1089/met.2018.0068. Epub 2019 Jan 8.
Abdominal obesity increases rapidly after middle age in Korean men, and there is an associated trend toward increasing levels of cardiovascular disease (CVD). The purpose of this study was to examine the effect of cardiorespiratory fitness (CRF) on arterial stiffness in men with abdominal obesity.
A total of 387 middle-aged men (ages 42-59 years) with abdominal obesity participated in this cross-sectional study. Abdominal obesity was defined as a waist circumference ≥90 cm. Arterial stiffness was derived from brachial/ankle pulse wave velocity (baPWV). A treadmill exercise test was conducted to directly assess CRF using the peak oxygen uptake. Blood glucose, blood pressure, lipids, C-related protein (CRP), and baPWV were measured at rest.
CRF was inversely associated with baPWV (r = -0.340, P = 0.014) and CRP level (r = -0.325, P = 0.026). In addition, high CRF was associated with a lower triglyceride level (r = -0.219, P = 0.030) and a higher high-density lipoprotein cholesterol level (r = 0.317, P = 0.019).
These results demonstrated that high CRF was inversely associated with arterial stiffness in men with abdominal obesity. These results suggest that maintaining a high level of CRF can help middle-aged men with abdominal obesity to improve blood factors related to CVD.
韩国男性中年后腹部肥胖迅速增加，心血管疾病（CVD）的发病率也呈上升趋势。本研究旨在探讨心肺功能（CRF）对腹部肥胖男性动脉僵硬的影响。
共有 387 名中年男性（年龄 42-59 岁）参加了这项横断面研究。腹部肥胖定义为腰围≥90cm。动脉僵硬由肱踝脉搏波速度（baPWV）得出。通过跑步机运动测试直接评估峰值摄氧量的 CRF。在休息时测量血糖、血压、血脂、C 反应蛋白（CRP）和 baPWV。
CRF 与 baPWV（r=-0.340，P=0.014）和 CRP 水平（r=-0.325，P=0.026）呈负相关。此外，高 CRF 与甘油三酯水平较低（r=-0.219，P=0.030）和高密度脂蛋白胆固醇水平较高（r=0.317，P=0.019）相关。
这些结果表明，高 CRF 与腹部肥胖男性的动脉僵硬呈负相关。这些结果表明，保持高 CRF 水平可以帮助中年腹部肥胖男性改善与 CVD 相关的血液因素。
