Eisner G
Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1978 Apr 7;206(1):33-8. doi: 10.1007/BF00411335.
The examination in optical section of sheep eyes, photocoagulated several months previously, shows a disturbed vitreous growth above the destroyed retinal areas (Figs. 2-4). The shape of the resulting deficiencies of vitreous structure (holes) suggests that the vitreous is produced by retinal elements and develops by appositional growth. Holes above lesions due to photocoagulation in an early developmental stage are longer (Fig. 1a; Fig. 2) than those above photocoagulations in later stages (Fig. 1b; Fig. 4). Holes above lesions with intensive retinal destruction (Fig. 2a; Fig. 4a) produce more important vitreous deficienceis than do weaker coagulations (Fig. 2b). Structural deficiencies, though extensive at first, become less important during further growth (Fig. 1c; Fig. 2c; Fig. 3 shows transverse sections at a deep and superficial level through the holes of Figure 2c), which is a sign that in the retinal scars a regeneration of elements producing vitreous occurs. Apart from the theoretical implications concerning the development of the vitreous, the results of our experiments should be considered when photocoagulating children.
对数月前进行过光凝治疗的羊眼进行光学切片检查,结果显示在被破坏的视网膜区域上方,玻璃体生长受到干扰(图2 - 4)。由此产生的玻璃体结构缺陷(孔洞)的形状表明,玻璃体是由视网膜成分产生的,并通过附加生长发育。早期发育阶段光凝损伤上方的孔洞(图1a;图2)比后期光凝损伤上方的孔洞(图1b;图4)更长。视网膜严重破坏损伤上方的孔洞(图2a;图4a)比较弱光凝损伤上方的孔洞(图2b)导致更严重的玻璃体缺陷。结构缺陷虽然起初范围广泛,但在进一步生长过程中变得不那么严重(图1c;图2c;图3展示了图2c中孔洞在深层和浅层的横切面),这表明在视网膜瘢痕中发生了产生玻璃体的成分的再生。除了有关玻璃体发育的理论意义外,在对儿童进行光凝治疗时,应考虑我们的实验结果。