Bracht Hendrik, Hafner Sebastian, Weiß Manfred
Anasthesiol Intensivmed Notfallmed Schmerzther. 2019 Jan;54(1):10-20. doi: 10.1055/a-0625-5492. Epub 2019 Jan 8.
Sepsis is a common disease in intensive care units worldwide, which is associated with relevant morbidity and mortality. Although massive research efforts have been made for decades, there is no specific therapy for sepsis to date. Decisive in the treatment of sepsis is the early diagnosis, because the outcome of the treated patients can be significantly improved by early elimination of the infection focus, the fastest possible administration of a broad, calculated antibiosis as well as the stabilization of the hemodynamic situation. A definition of the clinical picture of sepsis with high diagnostic sensitivity and specificity is therefore indispensable. This article describes the previously and the currently available definition of sepsis and gives an overview of the epidemiology of this disease.
脓毒症是全球重症监护病房中的常见疾病，与相关的发病率和死亡率相关。尽管数十年来已进行了大量研究工作，但迄今为止仍没有针对脓毒症的特效疗法。脓毒症治疗的关键在于早期诊断，因为通过尽早消除感染源、尽快给予广泛且合理的抗生素治疗以及稳定血流动力学状况，可显著改善患者的治疗结局。因此，具备高诊断敏感性和特异性的脓毒症临床表现定义不可或缺。本文介绍了脓毒症先前和当前可用的定义，并概述了该疾病的流行病学情况。
