Odabaş Faruk Ömer, Gümüş Haluk, Akkurt Halil Ekrem, Uca Ali Ulvi, Yilmaz Halim
Department of Neurology, SBÜ Konya Training and Research Hospital, Konya, Turkey.
Department of Neurology, Karatay University School of Medicine, Medicana Hospital, Konya, Turkey.
Noro Psikiyatr Ars. 2018 Dec;55(4):349-353. doi: 10.5152/npa.2017.19335. Epub 2018 Jul 5.
To investigate the effects of multiple sclerosis (MS) on male sexuality.
While 61 men with MS were included into the study group, 60 healthy men constituted the control group in the study. In MS patients, such parameters as functional status and depression levels were assessed with the Expanded Disability Status Scala (EDSS) and the Beck Depression Scale (BDS), other parameters such as pain levels, sexual function and quality of life (QoL) were evaluated with the Visual Analog Scala (VAS), the International Index of Erectile Function (IIEF) and the short form-36 (SF-36), respectively.
Patients with MS were classified as 45 with EDSS <5.5 and 19 with EDSS >5.5. Mean VAS and BDI scores patients with MS were found statistically significantly higher, compared with those of the controls (p<0.05). Mean IIEF and all sub-group scores of SF-36 of patients with MS were found to be statistically significantly lower, compared with those of the control group (p<0.05). Mean EDSS in patients with MS was 2.75±2.42. While there was a positive correlation between IIEF scores of patients with MS, and mean mental and physical components of SF-36, a negative correlation was found between IIEF scores in MS patients, and age, disease duration, number of attacks, number of marital years and scores of EDSS, VAS and BDI (p<0.00). When BDI ≥17 was accepted as the threshold for depression, the depression was detected in 62.5% of patients with MS and 11.7% of the controls (p<0.001).
Sexual functions are affected negatively in male patients with MS and seem to be associated with increased disability, pain and accompanying depression. Therefore, male patients with MS should also be evaluated with regard to sexual function, as well as disability during their follow-ups.
探讨多发性硬化症（MS）对男性性功能的影响。
本研究将61名患有MS的男性纳入研究组，60名健康男性作为对照组。对MS患者，使用扩展残疾状态量表（EDSS）和贝克抑郁量表（BDS）评估功能状态和抑郁水平等参数；使用视觉模拟量表（VAS）、国际勃起功能指数（IIEF）和简明健康调查问卷36项量表（SF - 36）分别评估疼痛水平、性功能和生活质量（QoL）等其他参数。
MS患者中，EDSS<5.5的有45例，EDSS>5.5的有19例。发现MS患者的平均VAS和BDI评分在统计学上显著高于对照组（p<0.05）。与对照组相比，MS患者的平均IIEF和SF - 36所有亚组评分在统计学上显著更低（p<0.05）。MS患者的平均EDSS为2.75±2.42。MS患者的IIEF评分与SF - 36的平均心理和生理成分之间呈正相关，而MS患者的IIEF评分与年龄、病程、发作次数、婚姻年限以及EDSS、VAS和BDI评分之间呈负相关（p<0.00）。当将BDI≥17作为抑郁阈值时，62.5%的MS患者和11.7%的对照组被检测出患有抑郁症（p<0.001）。
MS男性患者的性功能受到负面影响，似乎与残疾程度增加、疼痛及伴发的抑郁有关。因此，MS男性患者在随访期间除了评估残疾情况外，还应评估性功能。
