Bereuter Lukas, Gysin Mirco, Kueffer Thomas, Kucera Martin, Niederhauser Thomas, Fuhrer Jürg, Heinisch Paul, Zurbuchen Adrian, Obrist Dominik, Tanner Hildegard, Haeberlin Andreas
Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
ARTORG Center for Biomedical Engineering Research, University of Bern, Bern, Switzerland.
JACC Basic Transl Sci. 2018 Dec 31;3(6):813-823. doi: 10.1016/j.jacbts.2018.07.009. eCollection 2018 Dec.
Contemporary leadless pacemakers only feature single-chamber pacing capability. This study presents a prototype of a leadless dual-chamber pacemaker. Highly energy-efficient intrabody communication was implemented for wireless pacemaker synchronization. Optimal communication parameters were obtained by in vivo and ex vivo measurements in the heart and blood. The prototype successfully performed dual-chamber pacing in vivo. The presented wireless communication method may in the future also enable leadless cardiac resynchronization therapy.
当代无导线起搏器仅具备单腔起搏功能。本研究展示了一种无导线双腔起搏器的原型。为实现无线起搏器同步,采用了高能效的体内通信技术。通过在心脏和血液中的体内及体外测量获得了最佳通信参数。该原型在体内成功实现了双腔起搏。所提出的无线通信方法未来可能还会实现无导线心脏再同步治疗。