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Magnetoelectric Bio-Implants Powered and Programmed by a Single Transmitter for Coordinated Multisite Stimulation.

作者信息

Yu Zhanghao, Chen Joshua C, He Yan, Alrashdan Fatima T, Avants Benjamin W, Singer Amanda, Robinson Jacob T, Yang Kaiyuan

机构信息

Rice University, Houston, TX 77005, USA.

Rice University, Houston, TX 77005, USA; Baylor College of Medicine, Houston, TX 77030, USA.

出版信息

IEEE J Solid-State Circuits. 2022 Mar;57(3):818-830. doi: 10.1109/jssc.2021.3129993. Epub 2021 Dec 8.


DOI:10.1109/jssc.2021.3129993
PMID:36275505
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9581110/
Abstract

This paper presents a hardware platform including stimulating implants wirelessly powered and controlled by a shared transmitter for coordinated leadless multisite stimulation. The adopted novel single-transmitter, multiple-implant structure can flexibly deploy stimuli, improve system efficiency, easily scale stimulating channel quantity and relieve efforts in device synchronization. In the proposed system, a wireless link leveraging magnetoelectric effects is co-designed with a robust and efficient system-on-chip to enable reliable operation and individual programming of every implant. Each implant integrates a 0.8-mm chip, a 6-mm magnetoelectric film, and an energy storage capacitor within a 6.2-mm size. Magnetoelectric power transfer is capable of safely transmitting milliwatt power to devices placed several centimeters away from the transmitter coil, maintaining good efficiency with size constraints and tolerating 60-degree, 1.5-cm misalignment in angular and lateral movement. The SoC robustly operates with 2-V source amplitude variations that spans a 40-mm transmitter-implant distance change, realizes individual addressability through physical unclonable function IDs, and achieves 90% efficiency for 1.5-to-3.5-V stimulation with fully programmable stimulation parameters.

摘要

相似文献

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引用本文的文献

[1]
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Sci Rep. 2025-7-30

[2]
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[3]
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[4]
Magnetoelectrics for Implantable Bioelectronics: Progress to Date.

Acc Chem Res. 2024-10-15

[5]
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IEEE Trans Microw Theory Tech. 2023-5

[6]
Magnetoelectric Nanodiscs Enable Wireless Transgene-Free Neuromodulation.

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[7]
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[8]
Optimizing Cardiac Wireless Implant Communication: A Feasibility Study on Selecting the Frequency and Matching Medium.

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[9]
Design and Implementation of Multisite Stimulation System Using a Double-Tuned Transmitter Coil and Miniaturized Implants.

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本文引用的文献

[1]
Multiple neuronal networks coordinate mechanosensory behavior.

Elife. 2021-7-30

[2]
Wireless Power Delivery Techniques for Miniature Implantable Bioelectronics.

Adv Healthc Mater. 2021-9

[3]
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Sci Rep. 2021-1-21

[4]
MagNI: A Magnetoelectrically Powered and Controlled Wireless Neurostimulating Implant.

IEEE Trans Biomed Circuits Syst. 2020-12

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IEEE Trans Biomed Circuits Syst. 2020-12

[6]
Magnetoelectric Materials for Miniature, Wireless Neural Stimulation at Therapeutic Frequencies.

Neuron. 2020-6-8

[7]
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Nat Biomed Eng. 2020-2-19

[8]
Synchronized Biventricular Heart Pacing in a Closed-chest Porcine Model based on Wirelessly Powered Leadless Pacemakers.

Sci Rep. 2020-2-7

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Proc Natl Acad Sci U S A. 2020-1-23

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Nat Commun. 2019-12-17

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