Cherdyntseva T A, Egorov N S
Mikrobiologiia. 1988 Jul-Aug;57(4):574-8.
Among 24 fungal strains belonging to the genera Aspergillus, Acremonium and Verticillium, eight strains synthesized proteases with the coagulating activity. The most active strains producing such proteases were found among Aspergillus species. The fibrinolytic activity was detected in 12 strains of the fungi. Proteases with the fibrinolytic activity differed in their sensitivity to plasma inhibitors and the least sensitive proteases were found in A. niger and A. flavus. Some fungal strains synthesized proteases with the fibrinolytic activity exerting an indirect action. Such enzymes activated the conversion of blood profibrinolysin into fibrinolysin in a manner similar to that of staphylokinase, urokinase and trypsin.
在属于曲霉属、枝顶孢属和轮枝孢属的24种真菌菌株中，有8种菌株合成了具有凝血活性的蛋白酶。产生这种蛋白酶的活性最高的菌株存在于曲霉属菌种中。在12种真菌菌株中检测到了纤溶活性。具有纤溶活性的蛋白酶对血浆抑制剂的敏感性不同，最不敏感的蛋白酶存在于黑曲霉和黄曲霉中。一些真菌菌株合成了具有间接作用的纤溶活性蛋白酶。这些酶以类似于葡萄球菌激酶、尿激酶和胰蛋白酶的方式激活血液中纤维蛋白溶酶原向纤维蛋白溶酶的转化。
