Cokmez Hakan, Gulbahar Aysegul, Yigit Seyran, Aydin Cetin
Department of Obstetrics and Gynecology, Izmir Ataturk Training and Research Hospital, Turkey.
Department of Pathology, Izmir Ataturk Training and Research Hospital, Turkey.
J Pak Med Assoc. 2019 Jan;69(1):116-119.
Mature cystic teratoma (MCT) is the most common germ cell ovarian tumour, which accounts for 15-20% of all ovarian neoplasms. The frequency of MCT cases undergoing malignant transformation ranges from 0.17% to 2%. Our aim for presenting this case is to contribute to formation of an algorithm in the literature for the treatment and follow-up of MCT undergoing malignant transformation. A 38-year-old female patient presented to the emergency service with acute abdomen. The patient underwent salpingo-oophorectomy due to a prediagnosis of ovarian torsion with a dermoid cyst. Postoperative pathological examination reported oncocytic and tall columnar type papillary thyroid carcinoma arising on a mature cystic teratoma. During the follow up no local recurrences or metastases were identified in one-year. The rarity of MCT cases undergoing papillary type thyroid carcinoma transformation hinders the establishment of an algorithm for treatment and follow-up in literature.
成熟囊性畸胎瘤（MCT）是最常见的卵巢生殖细胞肿瘤，占所有卵巢肿瘤的15% - 20%。MCT发生恶性转化的频率在0.17%至2%之间。我们展示该病例的目的是为文献中形成MCT恶性转化的治疗和随访算法做出贡献。一名38岁女性患者因急腹症就诊于急诊。由于术前诊断为卵巢扭转伴皮样囊肿，患者接受了输卵管卵巢切除术。术后病理检查报告在成熟囊性畸胎瘤上发生了嗜酸性细胞和高柱状乳头状甲状腺癌。随访一年期间未发现局部复发或转移。MCT发生乳头状甲状腺癌转化的病例罕见，这阻碍了文献中治疗和随访算法的建立。
