Department of Hematology, Odense University Hospital.
Clin Nucl Med. 2019 Apr;44(4):319-320. doi: 10.1097/RLU.0000000000002448.
Heterotopic ossification (HO) is a benign condition characterized by the abnormal formation of mature lamellar bone in extraskeletal soft tissues. Most frequently, HO is observed around the hip joint after fractures or surgical procedures such as open reduction internal fixation or total hip arthroplasties. We are presenting a case of HO as detected by F-NaF PET/CT in a 68-year-old woman with multiple myeloma and a history of internal fixation of the right hip. Many previous publications have reported F-NaF uptake portraying calcification in soft tissue; the present report demonstrates the feasibility of F-NaF PET/CT to assess extraosseous calcification.
异位骨化(HO)是一种良性疾病,其特征是在骨骼外的软组织中形成成熟的板层骨。HO 最常发生在髋关节周围,发生于骨折或手术之后,如切开复位内固定或全髋关节置换术。我们报告了一例 68 岁女性多发性骨髓瘤患者的病例,该患者曾行右侧髋关节内固定术,F-NaF PET/CT 检测到 HO。许多先前的出版物都报道了 F-NaF 摄取显示软组织中的钙化;本报告展示了 F-NaF PET/CT 评估骨外钙化的可行性。