Katayama Osamu, Nishi Yuki, Osumi Michihiro, Takamura Yusaku, Kodama Takayuki, Morioka Shu
Department of Neurorehabilitation, Graduate School of Health Sciences, Kio University, 4-2-2 Umami-naka, Koryo-cho, Kitakatsuragi-gun, Nara 635-0832, Japan; Department of Rehabilitation, Watanabe Hospital, 45-2 Noma-kamikawada, Mihama-cho, Chita-gun, Aichi 470-3235, Japan.
Department of Neurorehabilitation, Graduate School of Health Sciences, Kio University, 4-2-2 Umami-naka, Koryo-cho, Kitakatsuragi-gun, Nara 635-0832, Japan.
Neurosci Lett. 2019 Apr 17;698:19-26. doi: 10.1016/j.neulet.2019.01.010. Epub 2019 Jan 6.
Sensorimotor incongruence (SMI) is associated with pathological pain, such as phantom limb pain. Additionally, patients with pathological pain and brain dysfunction typically present with movement disorders, including diminished voluntary control and increased variability in bimanual movement performance. In healthy subjects, SMI leads to dysesthesia and bimanual movement motor dysfunction. However, the brain localization of this activity remains unclear, particularly in SMI-induced dysesthesia and decrease in movement accuracy. In this study, 17 healthy participants were asked to perform repetitive flexion/extension exercises with their wrists in a congruent/incongruent position while viewing the activity in a mirror. Indeed, SMI induced dysesthesia and decreased bimanual movement accuracy. Moreover, beta band activities of the bilateral presupplementary (P < 0.01) and bilateral cingulate (P < 0.05) motor areas were decreased. Collectively, our findings indicate that SMI induces dysesthesia and movement disorders and reduces beta band activities in motor-related areas.
感觉运动不一致（SMI）与病理性疼痛相关，如幻肢痛。此外，患有病理性疼痛和脑功能障碍的患者通常会出现运动障碍，包括自主控制能力下降和双手运动表现的变异性增加。在健康受试者中，SMI会导致感觉异常和双手运动功能障碍。然而，这种活动在大脑中的定位仍不清楚，特别是在SMI引起的感觉异常和运动准确性下降方面。在本研究中，17名健康参与者被要求在观看镜子中的活动时，将手腕置于一致/不一致的位置进行重复性屈伸运动。事实上，SMI导致了感觉异常并降低了双手运动的准确性。此外，双侧辅助运动区（P<0.01）和双侧扣带回运动区（P<0.05）的β波段活动减少。总的来说，我们的研究结果表明，SMI会诱发感觉异常和运动障碍，并降低运动相关区域的β波段活动。
