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采用血管内方法治疗急性重症肺栓塞。

Treatment of the acute severe pulmonary embolism using endovascular methods.

作者信息

Keussen Inger E, Bursjoo Carina, Cwikiel Wojciech

机构信息

Department of Radiology, Lund University, Lund, Sweden.

Faculty of Medicine, Department of Clinical Sciences, Lund University, Lund, Sweden.

出版信息

Pol J Radiol. 2018 Jun 1;83:e248-e252. doi: 10.5114/pjr.2018.76785. eCollection 2018.

DOI:10.5114/pjr.2018.76785
PMID:30627243
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6323593/
Abstract

PURPOSE

To present a single-centre experience with endovascular treatment of patients with severe symptoms secondary to acute pulmonary embolism (PE).

MATERIAL AND METHODS

Twenty-five patients were treated due to contraindications or deficient effects of systemic thrombolytic therapy. The patients were treated with a combination of fragmentation and aspiration, only aspiration, or only fragmentation, and with catheter-directed thrombolytic therapy.

RESULTS

The saturation was improved following treatment in all patients, except in one where the procedure could not be completed. There were no immediate or late procedure-related complications.

CONCLUSIONS

Endovascular treatment of severe PE is a safe and efficient option in patients with failing effect or contraindication to systemic thrombolysis.

摘要

目的

介绍单中心对急性肺栓塞(PE)继发严重症状患者进行血管内治疗的经验。

材料与方法

25例患者因全身溶栓治疗的禁忌症或疗效不佳而接受治疗。患者接受了碎栓与抽吸联合、单纯抽吸或单纯碎栓治疗,并接受了导管定向溶栓治疗。

结果

除1例手术未完成的患者外,所有患者治疗后血氧饱和度均有所改善。无手术相关的即刻或晚期并发症。

结论

对于全身溶栓治疗效果不佳或有禁忌症的患者,血管内治疗严重PE是一种安全有效的选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a84b/6323593/048213c4a6be/PJR-83-76785-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a84b/6323593/d716c512f25c/PJR-83-76785-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a84b/6323593/048213c4a6be/PJR-83-76785-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a84b/6323593/d716c512f25c/PJR-83-76785-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a84b/6323593/048213c4a6be/PJR-83-76785-g002.jpg

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本文引用的文献

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Ultrasound-Assisted Catheter-Directed Thrombolysis for Submassive Pulmonary Embolism.超声辅助导管定向溶栓治疗亚大面积肺栓塞
Vasc Endovascular Surg. 2018 Apr;52(3):195-201. doi: 10.1177/1538574418757400. Epub 2018 Feb 13.
2
Safety of catheter-directed thrombolysis for massive and submassive pulmonary embolism: Results of a multicenter registry and meta-analysis.导管定向溶栓治疗大面积和次大面积肺栓塞的安全性:一项多中心注册研究和荟萃分析的结果
Catheter Cardiovasc Interv. 2017 Mar 1;89(4):754-760. doi: 10.1002/ccd.26900. Epub 2017 Feb 1.
3
Catheter-directed ultrasound-accelerated thrombolysis may be life-saving in patients with massive pulmonary embolism after failed systemic thrombolysis.
在全身溶栓治疗失败后,导管导向超声加速溶栓对大面积肺栓塞患者可能具有挽救生命的作用。
J Thromb Thrombolysis. 2016 Oct;42(3):322-8. doi: 10.1007/s11239-016-1370-3.
4
Treatment of Massive or Submassive Acute Pulmonary Embolism With Catheter-Directed Thrombolysis.导管定向溶栓治疗大面积或次大面积急性肺栓塞
Am J Cardiol. 2016 Mar 15;117(6):1014-20. doi: 10.1016/j.amjcard.2015.12.041. Epub 2015 Dec 31.
5
Endovascular Management of Acute Pulmonary Embolism Using the Ultrasound-Enhanced EkoSonic System.使用超声增强型EkoSonic系统对急性肺栓塞进行血管内治疗
Semin Intervent Radiol. 2015 Dec;32(4):384-7. doi: 10.1055/s-0035-1564707.
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Developments in the management and treatment of pulmonary embolism.肺栓塞管理与治疗的进展
Eur Respir Rev. 2015 Sep;24(137):484-97. doi: 10.1183/16000617.00006614.
7
Efficacy of rotational thrombectomy on the mortality of patients with massive and submassive pulmonary embolism.旋转式血栓切除术对大面积和次大面积肺栓塞患者死亡率的疗效。
J Card Surg. 2015 Apr;30(4):324-32. doi: 10.1111/jocs.12521. Epub 2015 Feb 13.
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Anatol J Cardiol. 2015 Jan;15(1):72-4. doi: 10.5152/akd.2014.5765. Epub 2014 Dec 25.
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Heart Lung Circ. 2015 Jan;24(1):46-54. doi: 10.1016/j.hlc.2014.06.014. Epub 2014 Jul 4.