Lyu H X, Wang Z R, Gao Y Q, Yu M, Li B Q, Zhang Z B
Department of Pathology, Hospital of Stomatology, Jilin University, Changchun 130021, China.
Department of TMD, Hospital of Stomatology, Jilin University, Changchun 130021, China.
Zhonghua Kou Qiang Yi Xue Za Zhi. 2019 Jan 9;54(1):10-16. doi: 10.3760/cma.j.issn.1002-0098.2019.01.003.
To investigate the incidence and proportion of salivary gland tumors in order to provide new thinking for clinical diagnosis and treatment. Collected 3 724 cases salivary gland tumors diagnosed by Pathology Department of Hospital of Stomatology, Jilin University from January 1961 to December 2016. The pathological diagnosis referred to the fourth edition of head and neck-salivary gland tumor histopathological classification standard of WHO. The database was established with Microsoft Excel and analyzed with SPSS 18.0. Made a retrospective analysis and comparison on the numbers of all cases in terms of types, site, gender and age and estimate the trend with the time interval of 8 years, and then make a judgement of the trend of salivary tumors. The benign tumors were more common than the malignant among all periods, the proportion of all tumors was about 2.92∶1; The top three benign tumors were polymorphous adenoma [73.78% (2 046/2 773)], Warthin tumor [15.80% (438/2 773)] and base cell adenoma [8.37% (232/2 773)]. Polymorphous adenoma took up 54.94% (2 046/3 724) of all tumors. The top three malignant tumors were mucous epidermoid carcinoma [31.44% (299/951)], adenoid cystic carcinoma [26.92% (256/951)] and adenocarcinoma [11.88% (113/951)]. As for sex, male female ratio was 0.83∶1. As for site, the pathogenic site of tumors was mainly in parotid gland [63.75% (2 374/3 724)], followed by palatal gland [16.50% (615/3 724)], then submandibular gland [12.67% (472/3 724)]; As for age, the common age was between 51 and 60 years old [23.74% (884/3 724)], followed by 41 to 50 years old [21.56%(803/3 724)]. The incidence of benign and malignant salivary gland tumor increased in the 56 years. Females showed a higher incidence. The majority tumors occurred in parotid gland. The most common salivary gland tumor was pleomorphic adenoma and the most common malignant tumor was mucous epidermoid carcinoma. The most common age was in 51-60 years old period.
为探讨涎腺肿瘤的发病率及构成比，为临床诊断与治疗提供新思路。收集吉林大学口腔医院病理科1961年1月至2016年12月诊断的3724例涎腺肿瘤病例。病理诊断参照WHO头颈部涎腺肿瘤组织病理学分类标准第四版。采用Microsoft Excel建立数据库，并用SPSS 18.0进行分析。对所有病例的数量按类型、部位、性别和年龄进行回顾性分析和比较，并以8年为时间间隔估计其变化趋势，进而判断涎腺肿瘤的变化趋势。各时期良性肿瘤均多于恶性肿瘤，两者比例约为2.92∶1；良性肿瘤前三位依次为多形性腺瘤[73.78%（2046/2773）]、沃辛瘤[15.80%（438/2773）]和基底细胞腺瘤[8.37%（232/2773）]。多形性腺瘤占所有肿瘤的54.94%（2046/3724）。恶性肿瘤前三位依次为黏液表皮样癌[31.44%（299/951）]、腺样囊性癌[26.92%（256/951）]和腺癌[11.88%（113/951）]。性别方面，男女比例为0.83∶1。部位方面，肿瘤好发部位主要在腮腺[63.75%（2374/3724）]，其次为腭腺[16.50%（615/3724）]，然后是下颌下腺[12.67%（472/3724）]；年龄方面，好发年龄在51～60岁[23.74%（884/3724）]，其次为41～50岁[占21.56%（803/3724）]。56年间涎腺良、恶性肿瘤发病率均呈上升趋势。女性发病率较高。多数肿瘤发生于腮腺。最常见的涎腺肿瘤是多形性腺瘤，最常见的恶性肿瘤是黏液表皮样癌。最常见的年龄在51～60岁年龄段。
