Vargas Pablo Agustin, Gerhard Ren, Araújo Filho Vergílius J F, de Castro Inês Vieira
Division of Oral Pathology, Faculty of Odontology of Piracicaba- UNICAMP, Hospital das Clínicas, Faculty of Medicine, University of São Paoulo, Brazil.
Rev Hosp Clin Fac Med Sao Paulo. 2002 Nov-Dec;57(6):271-6. doi: 10.1590/s0041-87812002000600005. Epub 2003 Feb 17.
Salivary gland tumors constitute a highly heterogeneous histopathologic group. There are few epidemiological studies of large series of benign and malignant salivary gland tumors in Brazil.
Hospital records of 124 patients with salivary gland tumors diagnosed from January 1993 to December 1999 were reviewed. The patients were analyzed according to gender, age, size, location, and histopathology of the tumor.
Patients with benign and malignant tumors presented with a mean age of 47.7 and 48.8 years, respectively. The frequency of benign tumors was 80% (n = 99) and malignant tumors 20% (n = 25). Tumors were localized in the parotid gland 71% (n = 88), in the submandibular gland 24% (n = 30), and in the minor salivary glands 5% (n = 6). The most common benign tumors were pleomorphic adenoma in 84% (n = 84) and Warthin's tumor in 13% (n = 13). Among malignant tumors, mucoepidermoid carcinoma was the most common in 52% (n = 13), adenoid cystic carcinoma occurred in 20% (n = 5), and carcinoma ex pleomorphic adenoma was detected in 12% (n = 3).
唾液腺肿瘤构成了一个高度异质性的组织病理学组群。在巴西,针对大量良性和恶性唾液腺肿瘤的流行病学研究较少。
回顾了1993年1月至1999年12月期间诊断为唾液腺肿瘤的124例患者的医院记录。根据患者的性别、年龄、肿瘤大小、位置和组织病理学对其进行分析。
良性和恶性肿瘤患者的平均年龄分别为47.7岁和48.8岁。良性肿瘤的发生率为80%(n = 99),恶性肿瘤为20%(n = 25)。肿瘤位于腮腺的占71%(n = 88),位于下颌下腺的占24%(n = 30),位于小唾液腺的占5%(n = 6)。最常见的良性肿瘤是多形性腺瘤,占84%(n = 84),沃辛瘤占13%(n = 13)。在恶性肿瘤中,黏液表皮样癌最为常见,占52%(n = 13),腺样囊性癌占20%(n = 5),多形性腺瘤恶变癌占12%(n = 3)。