Mahajan Rupali, Khinda Paramjit, Shewale Akhilesh, Ghotra Komaldeep, Bhasin Meenu Taneja, Bhasin Prashant
Department of Periodontics, National Dental College and Hospital, Dera Bassi, Punjab, India.
Department of Periodontics, Genesis Institute of Dental Sciences and Research, Ferozepur, Punjab, India.
J Indian Soc Periodontol. 2018 Nov-Dec;22(6):513-522. doi: 10.4103/jisp.jisp_88_18.
Guided tissue regeneration-based root coverage has emerged as a promising treatment modality in the treatment of gingival recession. A variety of nonresorbable and bioresorbable membranes have been successfully used. Among resorbable membranes, collagen has been extensively studied. Recently, a third generation barrier membrane derived from placenta has been introduced for periodontal regeneration.
The objective of the present study is to clinically compare the efficacy of placental membrane (Amnion) and collagen membrane (Healiguide) for the treatment of gingival recession.
Twelve patients having isolated bilateral gingival recession defects were included in the study and were divided into two groups randomly. Group I were treated by coronally positioned flap and amnion membrane and Group II were treated by coronally positioned flap and collagen membrane (Healiguide)™. Clinical parameters, including dental plaque index (PI), gingival index (GI), gingival recession depth, probing pocket depth, clinical attachment level, and gingival biotype, were recorded before surgery at baseline and then reevaluated at 3 and 6 months postoperatively.
Nonparametric test, i.e., Wilcoxon Signed-Ranks Test was used in the present study. Significance was reported at 95% confidence level.
The results of the present study revealed statistically no significant difference ( > 0.05) in dental PI improved, GI and probing pocket depth in both groups. Significant reduction in gingival recession defects and gain in clinical attachment level was observed in both the groups. Intergroup comparison of gingival recession defects and clinical attachment level yielded nonsignificant differences. However, a statistically significant increase ( < 0.05) in gingival tissue thickness was observed in Group II as compared to Group I.
Both membranes are equally efficacious in the treatment of gingival recession. More gingival tissue thickness (gingival biotype) enhancement was observed in sites treated with collagen membrane.
引导组织再生术式的根面覆盖已成为治疗牙龈退缩的一种有前景的治疗方式。多种不可吸收和可吸收膜已成功应用。在可吸收膜中，胶原已得到广泛研究。最近，一种源自胎盘的第三代屏障膜已被引入用于牙周再生。
本研究的目的是临床比较胎盘膜（羊膜）和胶原膜（Healiguide）治疗牙龈退缩的疗效。
12例患有孤立双侧牙龈退缩缺损的患者纳入本研究并随机分为两组。第一组采用冠向复位瓣联合羊膜治疗，第二组采用冠向复位瓣联合胶原膜（Healiguide）™治疗。在术前基线时记录临床参数，包括牙菌斑指数（PI）、牙龈指数（GI）、牙龈退缩深度、探诊深度、临床附着水平和牙龈生物型，然后在术后3个月和6个月重新评估。
本研究采用非参数检验，即Wilcoxon符号秩检验。显著性以95%置信水平报告。
本研究结果显示，两组在改善牙菌斑指数、牙龈指数和探诊深度方面在统计学上无显著差异（>0.05）。两组均观察到牙龈退缩缺损显著减少和临床附着水平增加。两组间牙龈退缩缺损和临床附着水平的比较无显著差异。然而，与第一组相比，第二组牙龈组织厚度在统计学上有显著增加（<0.05）。
两种膜在治疗牙龈退缩方面同样有效。在用胶原膜治疗的部位观察到更多牙龈组织厚度（牙龈生物型）增加。
