羊膜和绒毛膜同种异体移植联合冠向复位瓣治疗牙龈退缩的临床研究
Amnion and Chorion Allografts in Combination with Coronally Advanced Flap in the Treatment of Gingival Recession: A Clinical Study.
作者信息
Chakraborthy Sonali, Sambashivaiah Savita, Kulal Rithesh, Bilchodmath Shivaprasad
机构信息
Post Graduate Student, Department of Periodontology, Rajarajeswari Dental College and Hospital , Bangalore, India .
Professor and HOD, Department of Periodontology, Rajarajeswari Dental College and Hospital , Bangalore, India .
出版信息
J Clin Diagn Res. 2015 Sep;9(9):ZC98-ZC101. doi: 10.7860/JCDR/2015/12971.6572. Epub 2015 Sep 1.
BACKGROUND
Guided tissue regeneration (GTR) based root coverage using different allograft membranes has been utilized to correct gingival recession defects with promising results. Amnion and chorion allograft membranes of alternative origin derived from human placental tissue has been advocated in the treatment of gingival recession. However, chorion membrane has been used in combination with amnion membrane no study has compared these allograft membranes in the treatment of gingival recession. Therefore, the purpose of this study was to clinically evaluate and compare the efficacy of amnion membrane and chorion membrane in combination with coronally advanced flap in the treatment of gingival recessions.
MATERIALS AND METHODS
Twelve systemically healthy patients having at least 2 bilateral Miller's Class I or Class II gingival recession were recruited and coronally advanced flap was performed with amnion membrane or chorion membrane. Clinical parameters such as gingival Index, plaque index, length of the recession, width of the recession, width of keratinized gingiva, relative attachment level were evaluated at baseline, 3 and 6 months post-surgery.
RESULTS
The mean decrease in length of recession (LR) for Chorion site was 2.00±1.54mm and amnion site was 1.58±1.14mm. The gain in attachment level for amnion site was 2.17±1.53mm and for chorion site was 1.58±1.22mm. The total mean percentage of root coverage was 34% for chorion site and 22% for amnion site.
CONCLUSION
Both amnion membrane and chorion membrane has shown to be versatile allograft material to be used in the treatment of root coverage.
背景
使用不同的同种异体移植膜进行引导组织再生（GTR）以覆盖牙根，已被用于矫正牙龈退缩缺陷，并取得了令人满意的效果。源自人胎盘组织的羊膜和绒毛膜等不同来源的同种异体移植膜已被提倡用于治疗牙龈退缩。然而，绒毛膜一直是与羊膜联合使用，尚无研究比较这些同种异体移植膜在治疗牙龈退缩方面的效果。因此，本研究的目的是临床评估和比较羊膜和绒毛膜联合冠向复位瓣治疗牙龈退缩的疗效。
材料与方法
招募了12名全身健康、至少有2处双侧米勒I类或II类牙龈退缩的患者，分别使用羊膜或绒毛膜进行冠向复位瓣手术。在基线、术后3个月和6个月评估牙龈指数、菌斑指数、退缩长度、退缩宽度、角化龈宽度、相对附着水平等临床参数。
结果
绒毛膜组退缩长度（LR）的平均减少量为2.00±1.54mm，羊膜组为1.58±1.14mm。羊膜组附着水平的增加量为2.17±1.53mm，绒毛膜组为1.58±1.22mm。绒毛膜组牙根覆盖的总平均百分比为34%，羊膜组为22%。
结论
羊膜和绒毛膜均已证明是用于牙根覆盖治疗的通用同种异体移植材料。
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