Ghahroudi Amir Alireza Rasouli, Khorsand Afshin, Rokn Amir Reza, Sabounchi Sepideh Seyedzadeh, Shayesteh Yadollah Soleimani, Soolari Ahmad
Department of Periodontology, Faculty of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Department of Periodontology, Faculty of Dentistry, Hamedan University of Medical Sciences, Hamedan, Iran.
J Int Acad Periodontol. 2013 Oct;15(4):101-12.
The aim of the present double-blind, randomized, controlled study was to evaluate and compare the efficacy of amnion allograft and connective tissue graft in covering denuded root surfaces.
Seventy-one teeth in 22 patients with gingival recession were treated randomly with coronally displaced flap plus connective tissue graft (control group, n = 29 recessions in 10 patients) or coronally displaced flap plus amnion allograft (test group, n = 42 recessions in 12 patients). The amount of root coverage and clinical parameters (probing depth, recession depth, clinical attachment level, recession width, gingival width, and papilla dimensions) were measured at baseline and at 3 and 6 months postoperatively.
Average root coverage percentages after 6 months in the test and control groups were 67% (2.3 +/- 0.289 mm) and 54% (2.24 +/- 0.519 mm), respectively, with no statistically significant differences (p = 0.054). The changes in depth and width of recessions and in gingival width were significant 3 and 6 months after surgery compared to baseline (p = 0.000). Variations in the level of attachment and probing depths after 6 months were statistically significant in the test group compared to the control group (p = 0.002). Papilla dimensions were significantly correlated with root coverage (p = 0.00).
Amnion allograft might be a suitable alternative to connective tissue graft in procedures to cover denuded root surfaces and can reduce recession depth.
本双盲、随机、对照研究旨在评估和比较羊膜同种异体移植和结缔组织移植覆盖裸露牙根面的疗效。
将22例牙龈退缩患者的71颗牙齿随机分为两组，一组采用冠向复位瓣联合结缔组织移植（对照组，10例患者29处牙龈退缩），另一组采用冠向复位瓣联合羊膜同种异体移植（试验组，12例患者42处牙龈退缩）。在基线以及术后3个月和6个月时测量牙根覆盖量和临床参数（探诊深度、退缩深度、临床附着水平、退缩宽度、牙龈宽度和龈乳头尺寸）。
试验组和对照组术后6个月的平均牙根覆盖百分比分别为67%（2.3±0.289mm）和54%（2.24±0.519mm），差异无统计学意义（p = 0.054）。与基线相比，术后3个月和6个月时退缩深度和宽度以及牙龈宽度的变化具有统计学意义（p = 0.000）。与对照组相比，试验组术后6个月时附着水平和探诊深度的变化具有统计学意义（p = 0.002）。龈乳头尺寸与牙根覆盖显著相关（p = 0.00）。
在覆盖裸露牙根面的手术中，羊膜同种异体移植可能是结缔组织移植的合适替代方法，并且可以减少退缩深度。
