Kumari C Burnice Nalina, Ramakrishnan Thiagarajan, Devadoss Pradeep, Vijayalakshmi Rajaram, Alzahrani Khalid J, Almasri Mazen A, Al-Ahmari Manea Musa, Al Dira Hajar Saeed, Suhluli Malath, Bhati Ashok Kumar, Ahmad Zeeshan Heera, Raj A Thirumal, Bhandi Shilpa, Patil Shankargouda
Department of Periodontology and Implantology, Faculty of Dentistry, Meenakshi Academy of Higher Education and Research, Chennai 600095, India.
Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Meenakshi Academy of Higher Education and Research, Chennai 600095, India.
Biology (Basel). 2021 Dec 18;10(12):1348. doi: 10.3390/biology10121348.
The study aims to assess the efficacy of using collagen membrane in the treatment of distal periodontal defects of mandibular second molars following the removal of mesioangularly or horizontally impacted mandibular third molars surgically. Forty sites in twenty patients with bilaterally impacted mandibular third molars (mesioangular or horizontal) were considered for the study. In 20 test sites (Group A), after surgical removal of the mandibular third molar, a resorbable collagen membrane barrier was placed on the distal aspect of the mandibular second molar to cover the post-surgical bone defect. In the other control 20 sites (Group B), the same surgical procedure was repeated without placing any membrane barrier. The clinical parameters recorded were Oral Hygiene Index Simplified (OHI-S), Probing pocket depth (PPD), Clinical attachment level (CAL), and radiographic assessment of alveolar bone level (ABL). OHI-S score of most of the patients was observed to be satisfactory. Group A was observed to achieve a statistically significant reduction in PPD, CAL, and ABL gain compared to Group B. The improvements indicated that the use of collagen membrane facilitates early wound stabilization and promotes primary closure of the defect. This recovery is achieved through its unique property to assist fibrinogenesis over osteoconduction. Further longitudinal studies are needed to confirm the present findings.
本研究旨在评估在外科手术拔除近中倾斜或水平阻生的下颌第三磨牙后,使用胶原膜治疗下颌第二磨牙远中牙周缺损的疗效。本研究纳入了20例双侧下颌第三磨牙阻生(近中倾斜或水平阻生)患者的40个位点。在20个试验位点(A组),外科手术拔除下颌第三磨牙后,在下颌第二磨牙远中放置可吸收胶原膜屏障以覆盖术后骨缺损。在另外20个对照位点(B组),重复相同的外科手术操作,但不放置任何膜屏障。记录的临床参数包括简化口腔卫生指数(OHI-S)、探诊深度(PPD)、临床附着水平(CAL)以及牙槽骨水平的影像学评估(ABL)。观察到大多数患者的OHI-S评分令人满意。与B组相比,观察到A组在PPD、CAL和ABL增益方面有统计学意义的降低。这些改善表明,使用胶原膜有助于早期伤口稳定并促进缺损的一期闭合。这种恢复是通过其在促进纤维蛋白生成方面优于骨传导的独特特性实现的。需要进一步的纵向研究来证实目前的研究结果。