Johnson Adam P, Rattigan Deviney A, Pucci Michael J, Baliff Jeffrey P, Winter Jordan M, Yeo Charles J, Lavu Harish
Department of Surgery, The Jefferson Pancreas, Biliary and Related Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania.
Department of Pathology, Anatomy, & Cell Biology, Thomas Jefferson University, Philadelphia, Pennsylvania.
Case Rep Pancreat Cancer. 2015 Nov 1;1(1):16-21. doi: 10.1089/crpc.2015.29002.apj. eCollection 2015.
Correct preoperative diagnosis of hepatobiliary disease can be challenging-even with current advances in radiographical imaging, laboratory testing, and endoscopic evaluation. A 65-year-old female with painless jaundice and weight loss was found to have cholelithiasis complicated by the Mirizzi syndrome. A 71-year-old female with new-onset painless jaundice and impacted stone in the gallbladder neck was found to have a cholangiocarcinoma. A 70-year-old male with progressive painless jaundice and weight loss was found to have a pancreatic adenocarcinoma. Proper diagnosis and management of patients with painless jaundice can be difficult in the preoperative setting and may require surgical exploration to obtain a definitive diagnosis.
即使有当前放射影像学、实验室检测和内镜评估等方面的进展，肝胆疾病的术前正确诊断仍具有挑战性。一名65岁无痛性黄疸和体重减轻的女性被发现患有胆结石并发Mirizzi综合征。一名71岁新发无痛性黄疸且胆囊颈部有嵌顿结石的女性被发现患有胆管癌。一名70岁进行性无痛性黄疸和体重减轻的男性被发现患有胰腺腺癌。在术前阶段，对无痛性黄疸患者进行正确诊断和管理可能很困难，可能需要手术探查以获得明确诊断。
