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一例胆囊腺癌表现为Mirizzi综合征,患者无黄疸但近期体重减轻

A Case of Gallbladder Adenocarcinoma Presenting as Mirizzi Syndrome in a Non-Jaundiced Patient With Recent Weight Loss.

作者信息

Soca Gallego Lucia, Fritz Kristina, Dominguez Alvio J, Castilla Maria F

机构信息

Dr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University, Fort Lauderdale, USA.

General Surgery, HCA Florida Fawcett Hospital, Port Charlotte, USA.

出版信息

Cureus. 2022 Oct 19;14(10):e30459. doi: 10.7759/cureus.30459. eCollection 2022 Oct.

Abstract

There are many different types of gallbladder diseases, mainly resulting from inflammation. The long-term presence of an insult to the gallbladder leads to chronic inflammation, which is a nidus for complications such as Mirizzi syndrome and gallbladder cancer, both of which can become mimics of one another. Preoperative diagnosis of either gallbladder cancer or Mirizzi syndrome is often difficult, leading to late diagnosis and complicating the patient's treatment course. We report a case of a 65-year-old male who presented with abdominal pain and significant weight loss, with no physical evidence of jaundice and normal liver function. This was initially diagnosed as acute cholecystitis and Mirizzi syndrome before being diagnosed as gallbladder adenocarcinoma on final histology.

摘要

胆囊疾病有多种不同类型,主要由炎症引起。胆囊长期受到损害会导致慢性炎症,而慢性炎症是诸如Mirizzi综合征和胆囊癌等并发症的病灶,这两种疾病可能相互混淆。胆囊癌或Mirizzi综合征的术前诊断通常很困难,导致诊断延迟并使患者的治疗过程复杂化。我们报告一例65岁男性患者,其表现为腹痛和显著体重减轻,无黄疸体征且肝功能正常。该患者最初被诊断为急性胆囊炎和Mirizzi综合征,最终组织学检查确诊为胆囊腺癌。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ff58/9673054/5713db40b4b0/cureus-0014-00000030459-i01.jpg

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