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加速康复外科方案下术前体重减轻对减重手术结果的影响。

Influence of Preoperative Weight Loss on Outcomes of Bariatric Surgery for Patients Under the Enhanced Recovery After Surgery Protocol.

机构信息

Students' Scientific Group at 2nd Department of General Surgery, Jagiellonian University Medical College, Krakow, Poland.

2nd Department of General Surgery, Jagiellonian University Medical College, ul. Kopernika 21, 30-501, Krakow, Poland.

出版信息

Obes Surg. 2019 Apr;29(4):1134-1141. doi: 10.1007/s11695-018-03660-z.

Abstract

INTRODUCTION

The enhanced recovery after surgery (ERAS) protocol, which emphasizes preoperative interventions, is safely implemented in patients undergoing bariatric surgery. Patients are additionally encouraged to achieve weight loss preoperatively. We aimed to identify factors contributing to preoperative weight loss and assess their influence on outcomes of bariatric surgery among patients under the ERAS protocol.

MATERIALS AND METHODS

We reviewed a prospectively created database in two bariatric centers with 909 bariatric patients treated in accordance with ERAS principles. The database included demographic characteristics, factors related to the surgery or perioperative period, and short-term outcomes. Our endpoints included analyses of (1) factors potentially contributing to preoperative weight loss and (2) the influence of preoperative weight loss on short-term outcomes of bariatric treatment.

RESULTS

Diabetes mellitus (p = 0.007), obstructive sleep apnea (p < 0.001), and previous surgery (p = 0.012) were identified as predictors of preoperative weight loss. Steatohepatitis (p < 0.001) and respiratory disorder (p = 0.004) decreased the chance of achieving satisfactory preoperative body mass reduction. Except for operative time, early outcomes of bariatric surgery were not influenced by preoperative weight loss. Patients who achieved preoperative weight loss were less likely to be lost to follow-up (p = 0.023). Postoperative weight loss was better in patients who could lose ≥ 5% total weight preoperatively (p = 0.009).

CONCLUSION

Unsatisfactory preoperative weight loss among patients treated under ERAS principles is not associated with increased risk of complications. Satisfactory preoperative weight loss predicts superior postoperative weight loss and follow-up participation.

摘要

简介

强调术前干预的术后加速康复(ERAS)方案已安全应用于减重手术患者。此外,还鼓励患者在术前减轻体重。我们旨在确定促进术前体重减轻的因素,并评估其对 ERAS 方案下患者减重手术结果的影响。

材料与方法

我们回顾了两个符合 ERAS 原则的减重中心的前瞻性创建数据库,其中包含 909 例接受减重手术的患者。数据库包括人口统计学特征、与手术或围手术期相关的因素以及短期结果。我们的终点包括分析(1)可能促进术前体重减轻的因素,以及(2)术前体重减轻对减重治疗短期结果的影响。

结果

糖尿病(p=0.007)、阻塞性睡眠呼吸暂停(p<0.001)和既往手术史(p=0.012)被确定为术前体重减轻的预测因素。脂肪性肝炎(p<0.001)和呼吸障碍(p=0.004)降低了达到满意术前体重减轻的机会。除手术时间外,减重手术的早期结果不受术前体重减轻的影响。能够实现术前体重减轻的患者不太可能失访(p=0.023)。术前能够减轻≥5%总体重的患者术后体重减轻更好(p=0.009)。

结论

在接受 ERAS 方案治疗的患者中,不满意的术前体重减轻与并发症风险增加无关。满意的术前体重减轻预测术后体重减轻更好和随访参与度更高。

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