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超级肥胖老年人行减重手术后的中远期疗效。

Medium to long-term outcomes of bariatric surgery in older adults with super obesity.

机构信息

Center for Bariatric Surgery, Division of General Surgery, Department of Surgery, McGill University, Montreal, QC, Canada; Department of Clinical and Experimental Surgery, Medical Research Institute, Alexandria University, Alexandria, Egypt.

Center for Bariatric Surgery, Division of General Surgery, Department of Surgery, McGill University, Montreal, QC, Canada.

出版信息

Surg Obes Relat Dis. 2018 Apr;14(4):470-476. doi: 10.1016/j.soard.2017.11.008. Epub 2017 Nov 10.

Abstract

BACKGROUND

Indications and outcomes of bariatric surgery in older adults suffering from morbid obesity remain controversial. We aimed to evaluate safety and medium to long-term outcomes of bariatric procedures in this patient population.

SETTING

University Hospital, Canada.

METHODS

This is a single-center retrospective study of a prospectively collected database. We included patients aged ≥60 years who underwent sleeve gastrectomy, Roux-en-Y gastric bypass, or biliopancreatic diversion with duodenal switch between January 2006 and December 2014 and had at least 2 years of follow-up.

RESULTS

Of patients, 115 underwent bariatric surgeries (11 patients had 2 procedures). There were 66 were super-obese patients (body mass index>50 kg/m). Of patients, 74% had sleeve gastrectomy, 16% Roux-en-Y gastric bypass, and 8% underwent biliopancreatic diversion with duodenal switch. Mean age and body mass index were 63.3 ± 2.6 years and 51.7 ± 8.1 kg/m, respectively. Average follow-up time was 42 ± 19 months. At baseline, 78% had hypertension, 60% had type 2 diabetes, and 30% had obstructive sleep apnea. There was no 30-day mortality. Complication rate was 14% (n = 16): 2 leaks post-Roux-en-Y gastric bypass, 1 leak post-biliopancreatic diversion with duodenal switch, 1 obstruction post-sleeve gastrectomy, 1 bleeding requiring transfusion, 1 liver injury with bile leak, 2 port-site hernias, 1 myocardial infarction, 2 gastrojejunal strictures, 1 wound infection, 1 urinary tract infection, and 3 gastric reflux exacerbations. Mean percent excess weight loss at 2 years was 52.2 ± 23.8. Remission rates of hypertension, type-2 diabetes, and obstructive sleep apnea were 26%, 44%, and 38%, respectively.

CONCLUSION

Bariatric surgery is safe and effective in improving obesity-related co-morbidities in older patients suffering from morbid obesity. Age alone should not preclude older patients from getting the best bariatric procedure for obesity and related co-morbidities.

摘要

背景

在肥胖症患者中,老年患者接受减重手术的适应证和结果仍存在争议。我们旨在评估该患者人群中接受减重手术的安全性和中长期结果。

地点

加拿大某大学医院。

方法

这是一项单中心回顾性研究,对前瞻性收集的数据库进行了分析。我们纳入了 2006 年 1 月至 2014 年 12 月期间接受袖状胃切除术、Roux-en-Y 胃旁路术或胆胰分流加十二指肠转位术的年龄≥60 岁患者,且随访时间至少 2 年。

结果

共有 115 例患者接受了减重手术(11 例患者接受了 2 次手术)。其中 66 例为超级肥胖患者(体重指数>50kg/m2)。74%的患者接受了袖状胃切除术,16%的患者接受了 Roux-en-Y 胃旁路术,8%的患者接受了胆胰分流加十二指肠转位术。患者的平均年龄和体重指数分别为 63.3±2.6 岁和 51.7±8.1kg/m2。平均随访时间为 42±19 个月。基线时,78%的患者患有高血压,60%的患者患有 2 型糖尿病,30%的患者患有阻塞性睡眠呼吸暂停。术后 30 天内无死亡病例。并发症发生率为 14%(n=16):2 例 Roux-en-Y 胃旁路术后吻合口漏,1 例胆胰分流加十二指肠转位术后吻合口漏,1 例袖状胃切除术后梗阻,1 例需要输血的出血,1 例肝损伤伴胆漏,2 例切口疝,1 例心肌梗死,2 例胃空肠吻合口狭窄,1 例伤口感染,1 例尿路感染,3 例胃食管反流加重。术后 2 年的平均体重超标减轻百分比为 52.2±23.8。高血压、2 型糖尿病和阻塞性睡眠呼吸暂停的缓解率分别为 26%、44%和 38%。

结论

在肥胖症合并多种合并症的老年患者中,减重手术是安全且有效的,可改善肥胖相关的合并症。单纯年龄不应阻止老年患者接受最佳的减重手术来治疗肥胖症和相关合并症。

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