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Could genetic and epigenetic factors explain hypoxia tolerance and superior muscle performance of Sherpas at high-altitude?遗传和表观遗传因素能否解释夏尔巴人在高海拔地区的低氧耐受性和卓越肌肉表现？
J Physiol. 2019 Mar;597(5):1231-1232. doi: 10.1113/JP277593. Epub 2019 Jan 28.
2
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Epigenomics and human adaptation to high altitude.表观基因组学与人类对高海拔的适应。
J Appl Physiol (1985). 2017 Nov 1;123(5):1362-1370. doi: 10.1152/japplphysiol.00351.2017. Epub 2017 Aug 17.
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Metabolic adjustment to high-altitude hypoxia: from genetic signals to physiological implications.高原低氧环境下的代谢适应：从遗传信号到生理影响。
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本文引用的文献

1
UBC-Nepal expedition: peripheral fatigue recovers faster in Sherpa than lowlanders at high altitude.UBC-Nepal 考察队：在高海拔地区，夏尔巴人比低地人外周疲劳恢复更快。
J Physiol. 2018 Nov;596(22):5365-5377. doi: 10.1113/JP276599. Epub 2018 Oct 13.
2
Metabolic basis to Sherpa altitude adaptation.高原适应夏尔巴人的代谢基础。
Proc Natl Acad Sci U S A. 2017 Jun 13;114(24):6382-6387. doi: 10.1073/pnas.1700527114. Epub 2017 May 22.
3
Influence of a high-altitude hypoxic environment on human plasma microRNA profiles.高海拔缺氧环境对人血浆微小RNA谱的影响。
Sci Rep. 2015 Oct 15;5:15156. doi: 10.1038/srep15156.
4
King of the mountains: Tibetan and Sherpa physiological adaptations for life at high altitude.高山之王：藏族和夏尔巴人对高海拔生活的生理适应
Physiology (Bethesda). 2014 Nov;29(6):388-402. doi: 10.1152/physiol.00018.2014.
5
Human adaptation to the hypoxia of high altitude: the Tibetan paradigm from the pregenomic to the postgenomic era.人类对高海拔低氧环境的适应：从基因组时代之前到之后的藏族范例
J Appl Physiol (1985). 2014 Apr 1;116(7):875-84. doi: 10.1152/japplphysiol.00605.2013. Epub 2013 Nov 7.

Could genetic and epigenetic factors explain hypoxia tolerance and superior muscle performance of Sherpas at high-altitude?

作者信息

Guilherme João Paulo Limongi França, Silveira André Casanova

机构信息

Endurance Performance Research Group, Department of Sport, School of Physical Education and Sport, University of Sao Paulo, São Paulo, SP, Brazil.

出版信息

J Physiol. 2019 Mar;597(5):1231-1232. doi: 10.1113/JP277593. Epub 2019 Jan 28.

DOI:10.1113/JP277593
PMID:30632151
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6395412/
Abstract
摘要