1 Department of Oral and Maxillofacial Radiology, Graduate School, Tokyo Medical and Dental University , Tokyo , Japan.
2 Department of Oral Pathology, Graduate School, Tokyo Medical and Dental University , Tokyo , Japan.
Dentomaxillofac Radiol. 2019 May;48(4):20180311. doi: 10.1259/dmfr.20180311. Epub 2019 Feb 26.
To evaluate the diagnostic accuracies of 3T MRI in evaluating mandibular invasion of squamous cell carcinoma (SCC) in the oral cavity and to compare those with that of multidetector CT (MDCT).
41 cases with oral SCC examined by both 3T MRI and MDCT prior to surgery were included in this study. Intravenous contrast medium was administered in all examinations. Images were evaluated for the presence or absence of mandibular invasion and mandibular canal involvement by the tumour. For MRI, both two-dimensional (2D) fast spin echo (FSE) and three-dimensional (3D) volumetric interpolated breath-hold examination (VIBE) images were used for the evaluation. For MDCT, dental CT cross-sectional images were rused. The results were correlated with histopathological findings, and sensitivity and specificity of each imaging technique were calculated.DMFR prrof.
Histopathologically, 32 of 41 cases had mandibular invasion and 10 cases had mandibular canal involvement. For mandibular invasion, all three imaging techniques showed sensitivities of 100%. However, the specificities of 2D FSE (56%) and 3D VIBE (78%) were lower than that of MDCT (89%), although the differences were not significant. For mandibular canal involvement, whereas the sensitivities of all three imaging techniques were 100%, the specificities of 2D FSE, 3D VIBE and MDCT were 54, 62 and 85%, respectively. The specificity of 2D FSE was significantlylower than that of MDCT ( < 0.017).
In the evaluation of mandibular invasion, 3T MRI was not as accurate as MDCT. In particular, 2D FSE sequences showed significantly lower specificity than MDCT in evaluating the extent of mandibular invasion. The use of 3D VIBE sequence slightly improved the low specificity of 2D FSE sequences.
评估 3T MRI 评估口腔鳞状细胞癌（SCC）下颌骨侵犯的诊断准确性，并与多层螺旋 CT（MDCT）进行比较。
本研究纳入了 41 例术前同时接受 3T MRI 和 MDCT 检查的口腔 SCC 患者。所有检查均静脉注射对比剂。评估图像中是否存在肿瘤引起的下颌骨侵犯和下颌骨管受累。对于 MRI，使用二维（2D）快速自旋回波（FSE）和三维（3D）容积内插屏气检查（VIBE）图像进行评估。对于 MDCT，使用牙 CT 横断面图像。将结果与组织病理学发现相关联，并计算每种成像技术的敏感性和特异性。
组织病理学上，41 例中有 32 例有下颌骨侵犯，10 例有下颌骨管受累。对于下颌骨侵犯，所有三种成像技术的敏感性均为 100%。然而，2D FSE（56%）和 3D VIBE（78%）的特异性低于 MDCT（89%），尽管差异无统计学意义。对于下颌骨管受累，虽然三种成像技术的敏感性均为 100%，但 2D FSE、3D VIBE 和 MDCT 的特异性分别为 54%、62%和 85%。2D FSE 的特异性明显低于 MDCT（<0.017）。
在评估下颌骨侵犯方面，3T MRI 的准确性不如 MDCT。特别是 2D FSE 序列在评估下颌骨侵犯程度方面的特异性明显低于 MDCT。使用 3D VIBE 序列略微提高了 2D FSE 序列的低特异性。
