Department of dermatology, NHC/Ministry of Education/Liaoning Province Key Laboratory of Immunodermatology (China Medical University) The First Hospital of China Medical University, No. 155 Nanjing Bei Street, Heping District, Shenyang, Liaoning, P.R. China.
Dermatol Ther. 2019 Jul;32(4):e12815. doi: 10.1111/dth.12815. Epub 2019 Jan 28.
A female Cushing's syndrome patient had been suffering from extensive viral warts for months. She was diagnosed with flat warts, common warts and plantar warts. The plantar warts on her right foot were initially treated using local hyperthermia at 44°C for 30 min according to a defined protocol, followed by treatment targeting a common wart on her left thumb. In response to hyperthermia, the flat warts on her eyelid dissipated within 12 weeks, and when combined with a 1 week administration of imiquimod, the common warts and plantar warts completely disappeared within 8 weeks. There were no signs of recurrence and during this treatment her Cushing's syndrome was alleviated. This pioneer trial suggests that local hyperthermia may serve as an effective mean for treating multiple cutaneous warts under the conditions of a systemic immuno-compromised disease.
一位女性库欣综合征患者数月来一直患有广泛的病毒性疣。她被诊断为扁平疣、寻常疣和跖疣。根据既定方案，先用 44°C 的局部热疗对她右脚的跖疣进行 30 分钟治疗，然后对她左手拇指的寻常疣进行治疗。热疗后，她眼睑上的扁平疣在 12 周内消散，当与咪喹莫特治疗 1 周结合时，寻常疣和跖疣在 8 周内完全消失。没有复发迹象，在此治疗过程中，她的库欣综合征得到缓解。这项开创性试验表明，在系统性免疫功能受损疾病的情况下，局部热疗可能是治疗多种皮肤疣的有效方法。
