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采用个性化方法的腰椎前路椎间融合术:定制化是腰椎前路椎间融合手术植入物的未来发展方向吗?

Anterior Lumbar Interbody Fusion Using a Personalized Approach: Is Custom the Future of Implants for Anterior Lumbar Interbody Fusion Surgery?

作者信息

Mobbs Ralph J, Parr William C H, Choy Wen Jie, McEvoy Aidan, Walsh William R, Phan Kevin

机构信息

Faculty of Medicine, University of New South Wales (UNSW), Sydney, Australia; NeuroSpine Surgery Research Group (NSURG), Sydney, Australia; Department of Neurosurgery, Prince of Wales Hospital, Sydney, Australia.

Faculty of Medicine, University of New South Wales (UNSW), Sydney, Australia; Surgical & Orthopaedic Research Laboratories (S&ORL), UNSW, Sydney, Australia; 3DMorphic, Sydney, Australia.

出版信息

World Neurosurg. 2019 Apr;124:452-458.e1. doi: 10.1016/j.wneu.2018.12.144. Epub 2019 Jan 8.

Abstract

BACKGROUND

Spine surgery has the potential to benefit from the use of three-dimensional (3D) printing technology (additive manufacturing), particularly in cases of complex anatomic diseases. Custom devices have the potential to reduce operative times, reduce blood loss, provide immediate stability, and improve fusion rates.

CASE DESCRIPTION

A 34-year-old man presented with 3-year history of bilateral L5 radiculopathy caused by bilateral L5 pars defect, L5/S1 degenerative disc disease, and severe foraminal stenosis. Anterior lumbar interbody fusion surgery was determined to be the most efficacious method for distraction of the disc space to increase the foraminal volume and stabilization of the motion segment. Surgical decompression and reconstruction was performed in combination with a 3D printed custom interbody implant. Custom design features included corrective angulation to restore lumbar lordosis, preplanned screw holes in the 3D implant, and device end plate interface geometry designed to shape-match with the patient's end plate anatomy.

CONCLUSIONS

The use of patient-specific implants has reduced operative time significantly, which may offset costs of increased time spent preplanning the procedure. Surgical procedures can be preplanned using 3D models reconstructed from patient computed tomography and/or magnetic resonance imaging scans. Planning can be aided by 3D printed models of patient anatomy, which surgeons can use in training before performing complex procedures. When considering implants and prostheses, the use of 3D printing allows a superior anatomic fit for the patient compared with generic devices, with the potential to improve restoration of nonpathologic anatomy.

摘要

背景

脊柱手术有望受益于三维(3D)打印技术(增材制造),尤其是在复杂解剖疾病的病例中。定制器械有可能减少手术时间、减少失血、提供即时稳定性并提高融合率。

病例描述

一名34岁男性,因双侧L5椎弓根峡部裂、L5/S1椎间盘退变疾病和严重椎间孔狭窄导致双侧L5神经根病,病史3年。经判定,前路腰椎椎间融合术是扩大椎间隙以增加椎间孔容积并稳定运动节段的最有效方法。手术减压和重建结合使用了3D打印的定制椎间融合器植入物。定制设计特点包括用于恢复腰椎前凸的矫正角度、3D植入物上预先规划的螺钉孔以及设计成与患者终板解剖结构形状匹配的器械终板界面几何形状。

结论

使用定制植入物显著减少了手术时间,这可能抵消术前规划增加的时间成本。手术过程可使用从患者计算机断层扫描和/或磁共振成像扫描重建的3D模型进行预先规划。患者解剖结构的3D打印模型有助于规划,外科医生在进行复杂手术前可用于训练。在考虑植入物和假体时,与通用器械相比,3D打印的使用能为患者提供更优的解剖适配,有可能改善非病理性解剖结构的恢复。

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