Zhang Hong-Yan, Lu Sheng-Feng, Sun Zhi-Ling, Xu Gui-Hua
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2016 Jul;36(7):827-830.
To analyze document features and current research status of applying proteomics technology in acupuncture and moxibustion research, thereby further providing reference for further research and development in this area.
CNKI, Wangfang Data, CBM, PubMed, and Medline were included. Retrieved were literatures involving applying proteomics technology in acupunc- ture and moxibustion from January 2004 to December 2015. Document features and current research features were statistically analyzed using bibliometrics.
Totally 91 articles were included, 60 from journals, 8 conference theses, and 23 dissertations. The 60 articles were published in 47 kinds of journals, and 56 of them were published in core journals. Theories of acupuncture and moxibustion (correlated with meridians, zang-fu organs) and mechanism research were hotspots, involving 19 kinds of disease models (dominated as gastric mucosal lesion, cerebral ischemia, and spinal cord injury). Two- dimensional gel based electrophoresis technology was used in 51 articles (69. 86%).
Proteomics technology has been widely applied in the field of acupuncture and moxibustion research. It could promote researches on meridians and zang-fu organs correlated theories and mechanisms. The depth and breadth of the study is worth further widening.
分析蛋白质组学技术在针灸研究中的文献特征及研究现状，为该领域的进一步研究与发展提供参考。
检索中国知网、万方数据、中国生物医学文献数据库、PubMed及Medline，纳入2004年1月至2015年12月期间涉及蛋白质组学技术在针灸研究中的文献，采用文献计量学方法对文献特征及研究现状进行统计分析。
共纳入91篇文献，其中期刊论文60篇、会议论文8篇、学位论文23篇。60篇期刊论文发表于47种期刊，其中56篇发表于核心期刊。针灸理论（与经络、脏腑相关）及机制研究为热点，涉及19种疾病模型（以胃黏膜损伤、脑缺血、脊髓损伤为主）。51篇文献（69.86%）采用二维凝胶电泳技术。
蛋白质组学技术已广泛应用于针灸研究领域，可推动经络与脏腑相关理论及机制的研究，研究的深度和广度值得进一步拓展。
