Habib Sofia Noor, Lin Zhiheng, Puvanachandra Narman
Ophthalmology, Norfolk and Norwich University Hospitals NHS Foundation Trust, Norwich, UK.
Ophthalmology, James Paget University Hospitals NHS Foundation Trust, Great Yarmouth, UK.
BMJ Case Rep. 2019 Jan 10;12(1):bcr-2018-226738. doi: 10.1136/bcr-2018-226738.
This case report describes a 35-year-old Caucasian man who was referred to the glaucoma clinic with high intraocular pressure (IOP) after routine optometrist assessment. He was diagnosed with ocular hypertension (OHT) and the management plan was for monitoring without treatment. Three months later, he presented to the endocrine clinic with symptoms of Cushing's disease and was diagnosed with an adrenocorticotropic hormone secreting pituitary microadenoma. His symptoms preceded his presentation at both departments by 5 years. He underwent definitive surgical treatment of his adenoma via transsphenoidal resection. At 1-year follow-up in glaucoma clinic, it was noted that his IOP had normalised. Due to his high endogenous cortisol level at diagnosis, long disease duration, the pattern of IOP rise and subsequent normalisation after treatment, it is suggestive that his OHT is secondary to his Cushing's disease. There are infrequent reports of this association in published literature.
本病例报告描述了一名35岁的白种男性，在常规验光师评估后因高眼压被转诊至青光眼诊所。他被诊断为高眼压症（OHT），管理计划是进行监测而不进行治疗。三个月后，他因库欣病症状就诊于内分泌科，被诊断为分泌促肾上腺皮质激素的垂体微腺瘤。他在两个科室就诊前症状已出现5年。他通过经蝶窦切除术对腺瘤进行了确定性手术治疗。在青光眼诊所1年的随访中，发现他的眼压已恢复正常。由于他诊断时内源性皮质醇水平高、病程长、眼压升高模式以及治疗后随后恢复正常，提示他的高眼压症继发于库欣病。在已发表的文献中，这种关联的报道很少。
