玻利维亚一个农村社区中查加斯病导致的心脏发病率
Cardiac morbidity due to Chagas' disease in a rural community in Bolivia.
作者信息
Weinke T, Ueberreiter K, Alexander M
机构信息
Robert Koch-Institute, Fachgebiet Klinische Parasitologie, Berlin, West Germany.
出版信息
Epidemiol Infect. 1988 Dec;101(3):655-60. doi: 10.1017/s0950268800029538.
The prevalence of cardiac morbidity due to Chagas' disease was assessed in a rural community in Central Bolivia. Sixty-nine of 104 persons (66%) were seropositive to Trypanosoma cruzi by two serological methods. Two of 35 (6%) seronegative individuals presented with modest ECG alterations (left anterior hemiblock), but 21 of 69 (30%) seropositives showed modest and severe abnormalities (6 complete right bundle branch block, 2 polyfocal or frequent extrasystoles, 9 ischaemic ST alterations). A high percentage (56%) of domiciliary Triatoma infestans was infected with T. cruzi. There was a significant association between seropositivity and substandard housing. Priority preventive measures should thus include house improvement (to reduce bug infestation) and health education.
在玻利维亚中部的一个农村社区评估了恰加斯病所致心脏疾病的患病率。通过两种血清学方法，104人中的69人（66%）对克氏锥虫呈血清学阳性。35名血清学阴性个体中有2人（6%）出现轻度心电图改变（左前分支阻滞），但69名血清学阳性个体中有21人（30%）出现轻度和重度异常（6例完全性右束支传导阻滞、2例多灶性或频发期前收缩、9例缺血性ST段改变）。家栖的侵扰锥猎蝽感染克氏锥虫的比例很高（56%）。血清学阳性与住房条件差之间存在显著关联。因此，优先预防措施应包括改善住房（以减少臭虫滋生）和健康教育。
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