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[标准外科手术的证据:阑尾炎、憩室炎和胆囊炎]

[Evidence for standard surgical procedures: appendicitis, diverticulitis and cholecystitis].

作者信息

Tachezy M, Izbicki J R

机构信息

Klinik für Allgemein‑, Viszeral- und Thoraxchirurgie, Universitätsklinikum Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Deutschland.

出版信息

Chirurg. 2019 May;90(5):351-356. doi: 10.1007/s00104-018-0779-y.

Abstract

BACKGROUND

Acute appendicitis, cholecystitis and sigmoid diverticulitis are the most common inflammatory visceral surgical emergencies. According to the principles of evidence-based medicine, treatment methods and surgical indications should be constantly questioned and validated by high-quality clinical studies.

OBJECTIVE

To identify and classify the current evidence on surgical treatment of acute appendicitis, cholecystitis and sigmoid diverticulitis.

MATERIAL AND METHODS

Targeted literature search in Medline, the Cochrane Library and study registers (clinicaltrials.gov).

RESULTS AND CONCLUSION

The indications for surgery are changing due to increasing numbers of high-quality clinical studies. Conservative treatment seems to be feasible in the early stages. In contrast, many surgical steps have not yet been sufficiently validated. Furthermore, there is a great need for high-quality, prospective randomized clinical trials, so that promotion of studies and the study culture in surgery should continue to be of greatest interest.

摘要

背景

急性阑尾炎、胆囊炎和乙状结肠憩室炎是最常见的炎症性内脏外科急症。根据循证医学原则,治疗方法和手术指征应不断受到质疑,并通过高质量的临床研究加以验证。

目的

识别并分类当前关于急性阑尾炎、胆囊炎和乙状结肠憩室炎手术治疗的证据。

材料与方法

在医学文献数据库(Medline)、考克兰图书馆及研究注册库(clinicaltrials.gov)进行针对性文献检索。

结果与结论

由于高质量临床研究数量的增加,手术指征正在发生变化。保守治疗在早期似乎是可行的。相比之下,许多手术步骤尚未得到充分验证。此外,迫切需要高质量的前瞻性随机临床试验,因此对外科研究及研究文化的推广应继续给予最大关注。

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