Drexel University College of Medicine, Philadelphia, PA, USA.
HRC Fertility, Los Angeles, CA, USA.
Reprod Biol Endocrinol. 2019 Jan 13;17(1):5. doi: 10.1186/s12958-018-0448-5.
A mounting body of the literature suggests that environmental chemicals found in food and water could affect female reproduction. Many worldwide daily-used products have been shown to contain chemicals that could incur adverse reproductive outcomes in the perinatal/neonatal periods, childhood, adolescence, and even adulthood. The potential impact of Bisphenol A (BPA), Phthalates and Perfluoroalkyl substances (PFAS) on female reproduction, in particular on puberty, PCOS pathogenesis, infertility, ovarian function, endometriosis, and recurrent pregnancy loss, in both humans and animals, will be discussed in this report in order to provide greater clinician and public awareness about the potential consequences of these chemicals. The effects of these substances could interfere with hormone biosynthesis/action and could potentially be transmitted to further generations. Thus proper education about these chemicals can help individuals decide to limit exposure, ultimately alleviating the risk on future generations.
越来越多的文献表明，食物和水中的环境化学物质可能会影响女性生殖健康。许多全球日常使用的产品都被证实含有化学物质，这些化学物质可能会在围产期/新生儿期、儿童期、青春期甚至成年期导致不良的生殖后果。双酚 A (BPA)、邻苯二甲酸盐和全氟烷基物质 (PFAS) 对女性生殖的潜在影响，特别是对青春期、多囊卵巢综合征发病机制、不孕、卵巢功能、子宫内膜异位症和复发性流产，在人类和动物中，本报告将讨论这些化学物质的潜在后果，以便为临床医生和公众提供更多的认识。这些物质的影响可能会干扰激素的生物合成/作用，并可能传递给后代。因此，对这些化学物质进行适当的教育可以帮助个人决定限制接触，最终减轻对后代的风险。
