Bhatnagar Kaneeka, Narang Vikram, Garg Bhavna, Sood Neena
Senior Resident, Dept of Pathology, Dayanand Medical College and Hospital, Ludhiana, India.
Dept. of Pathology, Dayanand Medical College and Hospital, Ludhiana, India.
Iran J Pathol. 2018 Summer;13(3):372-376. Epub 2018 Sep 12.
Xanthogranulomatous oophoritis is an uncommon, non-neoplastic, chronic process in which the affected organ is destroyed by massive cellular infiltration of foamy histiocytes admixed with multinucleated giant cells, plasma cells, fibroblasts, neutrophils, and foci of necrosis. The etiology of this entity is unknown, but it shares histopathological findings similar to those of xanthogranulomatous change occurring in various organs, including the gallbladder and kidney. The current case was a 20-year-old female presenting with a tubo-ovarian mass with suspicion of malignancy on clinicoradiological findings and final diagnosis of xanthogranulomatous oophritis established on histopathology. Clinically and radiologically, xanthogranulomatous oophritis mimics tumor of the ovary and fallopian tube, thereby making it an important entity. A vigilant histopathological evaluation is important to diagnose the disease.
黄色肉芽肿性卵巢炎是一种罕见的非肿瘤性慢性病变，在此病变中，受累器官因大量泡沫状组织细胞与多核巨细胞、浆细胞、成纤维细胞、中性粒细胞混合浸润以及坏死灶而被破坏。该病变的病因尚不清楚，但它具有与包括胆囊和肾脏在内的各种器官中发生的黄色肉芽肿性改变相似的组织病理学表现。本例为一名20岁女性，临床影像学检查发现附件区肿物，怀疑为恶性肿瘤，最终经组织病理学确诊为黄色肉芽肿性卵巢炎。在临床和影像学上，黄色肉芽肿性卵巢炎酷似卵巢和输卵管肿瘤，因此它是一个重要的病变。警惕的组织病理学评估对于诊断该疾病很重要。
