Briki Raja, Cherif Ons, Bannour Badra, Hidar Samir, Boughizane Sassi, Khairi Hedi
Department of Gynecology and Obstetrics, Farhat Hached's University Hospital, Sousse, Tunisia.
Pan Afr Med J. 2018 Aug 9;30:268. doi: 10.11604/pamj.2018.30.268.16208. eCollection 2018.
Although it is known that breast cancer can metastasize to many organ sites, metastasis to the uterus is uncommon and usually occurs during widespread metastatic disease. Lobular carcinoma is not the most common histological subtypes of breast carcinoma, but it is the most frequent histologic type that causes gastrointestinal, gynecological and peritoneal metastases. The main symptoms of the uterine metastasis depend on the anatomic involvement site. Abnormal uterine bleeding is by far the most important symptom.We highlight the importance of the follow up of patient with breast cancer. A rapid endometrial sampling for confirmation of the diagnosis, should be performed when the routine gynecological follow-up revealed any abnormality. We report two original observations of endometrium metastases of invasive lobular carcinoma of the breast which we detected during follow-up.
尽管已知乳腺癌可转移至多个器官部位，但转移至子宫并不常见，通常发生在广泛转移性疾病期间。小叶癌并非乳腺癌最常见的组织学亚型，但却是导致胃肠道、妇科和腹膜转移最常见的组织学类型。子宫转移的主要症状取决于解剖受累部位。异常子宫出血是迄今为止最重要的症状。我们强调了对乳腺癌患者进行随访的重要性。当常规妇科随访发现任何异常时，应进行快速子宫内膜取样以确诊。我们报告了在随访期间检测到的两例原发性乳腺浸润性小叶癌子宫内膜转移病例。
