Jeon Younghoon, Lee Heryim
Department of Anesthesiology and Pain Medicine, School of Dentistry, Kyungpook National University, Daegu, Republic of Korea.
J Dent Anesth Pain Med. 2018 Dec;18(6):333-337. doi: 10.17245/jdapm.2018.18.6.333. Epub 2018 Dec 28.
Ramsay Hunt syndrome is a type of acute herpes zoster, which occurs by reactivation of the varicella-zoster virus at the geniculate ganglion. Clinical presentation of Ramsay Hunt syndrome includes a vesicular rash on the ear (herpes zoster oticus) or in the oral mucosa accompanied by acute peripheral facial nerve paralysis. Other cranial nerves such as V, IX, XI, and XII are often involved. Additional variability of the clinical picture of Ramsay Hunt syndrome is produced by varying patterns of skin involvement explained by individual anastomoses between cranial and cervical nerves. Combination treatment containing anti-viral agents and steroids is recommended for the treatment of Ramsay Hunt syndrome. Additionally, early diagnosis of Ramsay Hunt syndrome is a crucial factor to improve damaged nerves in Ramsay Hunt syndrome, which initiates treatment as soon as possible.
拉姆齐·亨特综合征是一种急性带状疱疹,由膝状神经节处的水痘-带状疱疹病毒再激活引起。拉姆齐·亨特综合征的临床表现包括耳部(耳部带状疱疹)或口腔黏膜出现水疱性皮疹,并伴有急性周围性面神经麻痹。其他颅神经如V、IX、XI和XII常受累。由于颅神经和颈神经之间的个体吻合导致皮肤受累模式不同,从而使拉姆齐·亨特综合征的临床表现具有额外的变异性。建议采用抗病毒药物和类固醇联合治疗拉姆齐·亨特综合征。此外,早期诊断拉姆齐·亨特综合征是改善该综合征中受损神经的关键因素,应尽早开始治疗。