Department of Dermatology, Allergology and Phlebology, Klinikum Bremerhaven Reinkenheide, Postbrookstrasse 103, Bremerhaven, Germany.
J Dtsch Dermatol Ges. 2012 Apr;10(4):238-44. doi: 10.1111/j.1610-0387.2012.07894.x. Epub 2012 Mar 19.
Ramsay Hunt syndrome is defined as herpes zoster oticus associated with an acute peripheral facial nerve paresis and quite often with other cranial nerve lesions. The combination of motor, sensory and autonomic involvement leads to a variety of neurological damage patterns, i. e. facial muscle paresis, hearing and balance disorders, sensory problems and disturbances of taste as well as lacrimal and nasal secretion. Additional variability of the clinical picture of Ramsay Hunt syndrome is produced by varying patterns of skin involvement explained by individual anastomoses between cranial and cervical nerves. Knowledge of these findings and an early diagnosis of Ramsay Hunt syndrome are important as prognosis of cranial nerve damage depends on the time at which acyclovir-corticosteroid therapy is started.
拉姆齐亨特综合征定义为与急性周围性面神经麻痹相关的耳部带状疱疹,且常伴有其他颅神经病变。运动、感觉和自主神经受累的组合导致多种神经损伤模式,即面部肌肉瘫痪、听力和平衡障碍、感觉问题以及味觉和泪液、鼻液分泌紊乱。拉姆齐亨特综合征的临床表现的额外变异性是由颅神经和颈神经之间的个体吻合模式解释的不同皮肤受累模式产生的。了解这些发现并早期诊断拉姆齐亨特综合征很重要,因为颅神经损伤的预后取决于开始使用阿昔洛韦-皮质类固醇治疗的时间。