Tianjin Centers for Disease Control and Prevention, No. 6 Huayue Road, Hedong District, Tianjin, 300011, People's Republic of China.
Department of Occupational and Environmental Health, School of Public Health, Peking University, No. 38 Xueyuan Road, Haidian District, Beijing, 100191, People's Republic of China.
Environ Sci Pollut Res Int. 2019 Mar;26(7):6931-6938. doi: 10.1007/s11356-019-04123-3. Epub 2019 Jan 14.
Currently, the quantitative assessment of the public excess risk for the update of the air quality guidelines only considered the mortality and morbidity without disease burden indicators. To provide evidences for the update of air quality guidelines and the policy analysis of air control, a simple framework to identify the excess disease burden of PM was used in this study. Daily data on PM, meteorological factors, and deaths were collected in this 10-year (2001-2010) time series study in Tianjin, China. The excess disease burden advanced by PM was assessed when the PM levels exceeded the expected levels. Generalized additive model was used to estimate the associations of PM with mortality and years of life lost (YLL). Our study found that the exposure of PM was associated with the increasing of mortality and YLL in different diseases. The excess deaths and YLL of different diseases advanced by PM when the PM levels exceeded the expected levels were high and showed a decreasing trend from 2001 to 2010. The annual deaths and YLL standardized per million population advanced by PM when the annual PM levels exceeded the China national ambient air quality secondary standard targets (70 μg/m) and WHO guideline (20 μg/m) were 126 persons, 2670 person years and 260 persons, 5449 person years, respectively. This study may provide a simple framework to identify the excess disease burden of PM and provide basic and intuitive evidences to update the air quality guidelines. Furthermore, these findings may also provide decisionmakers with intuitive quantitative information for policymaking and emphasize health considerations in air quality policy discussions.
目前,空气质量指南更新的公众超额风险定量评估仅考虑了死亡率和发病率,而没有疾病负担指标。为了为空气质量指南的更新和空气控制政策分析提供依据,本研究采用了一种简单的框架来识别 PM 的超额疾病负担。本研究在天津进行了为期 10 年(2001-2010 年)的时间序列研究,收集了 PM、气象因素和死亡的每日数据。当 PM 水平超过预期水平时,评估了 PM 引起的超额疾病负担。使用广义加性模型估计 PM 与死亡率和寿命损失年(YLL)之间的关联。我们的研究发现,PM 暴露与不同疾病的死亡率和 YLL 增加有关。当 PM 水平超过预期水平时,不同疾病的超额死亡和 YLL 较高,并呈下降趋势从 2001 年到 2010 年。当每年的 PM 水平超过中国国家环境空气质量二级标准目标(70μg/m)和世卫组织指南(20μg/m)时,每年每百万人因 PM 而增加的死亡人数和 YLL 分别为 126 人、2670 人年和 260 人、5449 人年。本研究可为识别 PM 的超额疾病负担提供一种简单的框架,并为更新空气质量指南提供基本和直观的依据。此外,这些发现还可以为决策者提供直观的定量信息,以进行决策,并在空气质量政策讨论中强调健康考虑因素。