State Key Laboratory of Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China; State Key Laboratory of Organ Failure Research, Department of Biostatistics, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou 510515, China.
State Key Laboratory of Organ Failure Research, Department of Biostatistics, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health, Southern Medical University, Guangzhou 510515, China.
Sci Total Environ. 2016 Dec 15;573:1566-1572. doi: 10.1016/j.scitotenv.2016.09.014. Epub 2016 Sep 7.
Previous studies have mainly used mortality or morbidity as the health outcome to examine the air pollution-health association. Little evidence is available on relationships between air pollutants and years of life lost (YLL). We aimed to estimate the YLL from cardiovascular mortality due to air pollution. Daily data on weather and air pollutants and individual data of all registered deaths for years 2004-2007 were obtained in Guangzhou, China. The generalized additive model was used to assess the YLL associated with 10μg/m increases in NO, SO and PM. We found that the mean daily YLL was 248, 87.5 and 73.7 for deaths from cardiovascular disease (CVD), stroke and ischemic heart disease (IHD), respectively. A significant linear correlation was observed between air pollution and YLL due to cardiovascular disease. The effects of air pollutants on YLL were immediate and lasted for two days. A 10μg/m increase above the corresponding threshold of 55.6μg/m, 40.4μg/m and 0μg/m in NO, PM and SO was related to YLL increase of 1.8 (95% CI: 0.8-2.9), 2.8 (1.7-3.8) and 2.6 (1.2-4.0) years at lag 0-1days for CVD, respectively. The estimates of YLL associated with NO and PM were higher in men than women. The air pollutants-related YLL was higher among young people and those with low education level, compared to the elderly and those with high education level, respectively. These findings confirmed YLL provides a complementary strategy for assessing the health effect of air pollution. This study underscores the necessity of the reduction of air pollution benefiting public health.
先前的研究主要使用死亡率或发病率作为健康结果来检验空气污染与健康之间的关系。关于空气污染物与生命损失年数（YLL）之间的关系，证据有限。我们旨在评估因空气污染导致的心血管疾病死亡的 YLL。在中国广州，我们获取了 2004-2007 年期间的天气和空气污染物的每日数据以及所有登记死亡者的个人数据。我们使用广义加性模型评估了与 10μg/m³的 NO、SO 和 PM 增加相关的 YLL。我们发现，心血管疾病（CVD）、中风和缺血性心脏病（IHD）导致的每日平均 YLL 分别为 248、87.5 和 73.7。我们观察到空气污染与心血管疾病导致的 YLL 之间存在显著的线性相关性。空气污染物对 YLL 的影响是即时的，持续两天。NO、PM 和 SO 的相应阈值 55.6μg/m³、40.4μg/m³和 0μg/m³之上，每增加 10μg/m³，与 CVD 的 YLL 增加 1.8（95%CI：0.8-2.9）、2.8（1.7-3.8）和 2.6（1.2-4.0）年相关，滞后 0-1 天。NO 和 PM 与 YLL 相关的估计值在男性中高于女性。与老年人和高学历者相比，年轻人和低学历者的空气污染物相关的 YLL 更高。这些发现证实了 YLL 为评估空气污染对健康的影响提供了一种补充策略。本研究强调了减少空气污染物以造福公众健康的必要性。
