Genetic Counseling Department, Arcadia University, Glenside, PA, USA.
Division of Clinical Genetics, St. Christopher's Hospital for Children, Philadelphia, PA, USA.
Qual Life Res. 2019 Jun;28(6):1457-1464. doi: 10.1007/s11136-019-02102-2. Epub 2019 Jan 14.
We sought to examine the prevalence of depression and anxiety in adults with skeletal dysplasias, and to assess any correlations with pain.
Participation was via an anonymous REDCap survey, which consisted of sociodemographic questions followed by the brief pain inventory-short form (BPI-SF), patient health questionnaire-8 (PHQ-8), and generalized anxiety disorder-7 (GAD-7) questionnaires. These assessed pain, depression, and anxiety respectively.
Of the 336 usable responses, 16.1% scored 10 or greater on the PHQ-8 consistent with current depression while 17.3% scored 10 or greater on the GAD-7 consistent with current anxiety. The majority of participants (76.2%) experienced pain, which was significantly associated with prior mental health diagnoses (p < 0.05). A total of 34% reported either a prior diagnosis of depression or scored 10 or greater on the PHQ-8, and 31% reported either a prior diagnosis of anxiety or scored 10 or greater on the GAD-7.
This study identified a substantial percentage of individuals with mental health concerns as well as pain in the adult skeletal dysplasia population. Further research is warranted to investigate barriers to service or treatment of mental health disorders as well as pain management.
我们旨在研究骨骼发育不良的成年人中抑郁和焦虑的患病率,并评估其与疼痛的相关性。
通过匿名 REDCap 调查参与研究,该调查由社会人口统计学问题以及简短疼痛量表(BPI-SF)、患者健康问卷-8(PHQ-8)和广泛性焦虑障碍-7(GAD-7)问卷组成。这些问卷分别评估疼痛、抑郁和焦虑。
在 336 份可用回复中,16.1%的 PHQ-8 评分≥10,提示存在当前抑郁,而 17.3%的 GAD-7 评分≥10,提示存在当前焦虑。大多数参与者(76.2%)经历疼痛,且疼痛与先前的心理健康诊断显著相关(p<0.05)。共计 34%的参与者报告有抑郁的既往诊断或 PHQ-8 评分≥10,31%的参与者报告有焦虑的既往诊断或 GAD-7 评分≥10。
本研究在骨骼发育不良的成年人群中发现了相当比例的存在心理健康问题以及疼痛的患者。有必要进一步研究服务或治疗心理健康障碍以及疼痛管理方面的障碍。