Tanner Kristine, Anderson Catherine, Smith Marshall E
1 Department of Communication Disorders, Brigham Young University, Provo, UT, USA.
2 Division of Otolaryngology-Head & Neck Surgery, The University of Utah, Salt Lake City, UT, USA.
Ann Otol Rhinol Laryngol. 2019 Apr;128(4):345-351. doi: 10.1177/0003489418823797. Epub 2019 Jan 14.
: People with subglottic stenosis (SGS) may experience laryngeal symptoms that pose significant challenges to management. This study surveyed the use and effects of nebulized treatments on laryngeal symptoms in a large cohort of adults with SGS.
: A survey of nebulized treatment practices was distributed to an online international community of over 2000 members; 316 individuals (298 female, 1 male, 17 declined to specify; age 25+ years) completed the survey.
: Nearly half (144) of participants had tried a nebulizer in the past. Among those, half currently used nebulized treatments; the majority used these treatments regularly and for greater than 1 year. The most frequently reported treatments included isotonic saline (0.9% NaCl) or hypertonic saline (3% NaCl). Symptoms improved by these treatments included thick mucus (69%), cough (57%), throat dryness (31%), stridor (28%), and voice (15%). The most frequently reported limitations to nebulizer use included time, noise, and portability.
: Among those individuals with SGS who have tried nebulized treatments, nearly half experienced relief from secondary laryngeal symptoms. Additional efficacy research is needed, particularly with respect to treatment type and dosage. The results are encouraging given the adverse impact these laryngeal symptoms can have on activities of daily living and quality of life.
声门下狭窄(SGS)患者可能会出现喉部症状,这给治疗带来了重大挑战。本研究调查了雾化治疗在一大群成年SGS患者中对喉部症状的使用情况和效果。
向一个拥有2000多名成员的在线国际社区发放了一份关于雾化治疗实践的调查问卷;316人(298名女性,1名男性,17人拒绝说明;年龄25岁及以上)完成了调查。
近一半(144名)参与者过去曾尝试过雾化器。其中,一半人目前正在使用雾化治疗;大多数人定期使用这些治疗且使用时间超过1年。最常报告的治疗方法包括等渗盐水(0.9%氯化钠)或高渗盐水(3%氯化钠)。这些治疗改善的症状包括浓稠黏液(69%)、咳嗽(57%)、喉咙干燥(31%)、喘鸣(28%)和声音问题(15%)。最常报告的雾化器使用限制包括时间、噪音和便携性。
在尝试过雾化治疗的SGS患者中,近一半人的继发性喉部症状得到缓解。需要进行更多的疗效研究,特别是关于治疗类型和剂量的研究。考虑到这些喉部症状会对日常生活活动和生活质量产生不利影响,这些结果令人鼓舞。