Venkat Arthi G, Baynes Kimberly, Lowder Careen Y, Srivastava Sunil K, Sharma Sumit
Ophthalmic Surg Lasers Imaging Retina. 2019 Jan 1;50(1):53-55. doi: 10.3928/23258160-20181212-09.
A woman with a past medical history of radiation and chemotherapy for multiple malignancies presented with bilateral, multifocal, elevated chorioretinal lesions associated with vitritis. The differential diagnosis included endogenous endophthalmitis and metastatic disease. Her extensive medical history and ill appearance at presentation in concert with vitritis and subretinal lesions was concerning for endogenous endophthalmitis. Although her vitreous sample was negative, her blood cultures were positive for Nocardia kropenstedtii and Nocardia farcinica. She was started on broad-spectrum antibiotic coverage but had brain lesions on presentation and ultimately passed away. This is the first reported case of Nocardia endophthalmitis in the setting of systemic N. kroppenstedtii infection. [Ophthalmic Surg Lasers Imaging Retina. 2019;50:53-55.].
一名有多种恶性肿瘤放疗和化疗病史的女性,出现双侧、多灶性、隆起的脉络膜视网膜病变并伴有玻璃体炎。鉴别诊断包括内源性眼内炎和转移性疾病。她既往复杂的病史以及就诊时不佳的外观表现,再加上玻璃体炎和视网膜下病变,令人怀疑为内源性眼内炎。尽管她的玻璃体样本检测结果为阴性,但血培养显示克氏诺卡菌和豚鼠诺卡菌呈阳性。她开始接受广谱抗生素治疗,但就诊时已出现脑部病变,最终不幸去世。这是首例在系统性克氏诺卡菌感染背景下发生诺卡菌性眼内炎的报告病例。[《眼科手术、激光与视网膜影像》。2019年;50:53 - 55。]