Foglia Francesco, Ambrosino Annalisa, Greco Giuseppe, Chianese Annalisa, Zannella Carla, Cinone Francesca, Reginelli Alfonso, Giordano Diego Sandro, Tortorella Giovanni, Laieta Maria Teresa, De Filippis Anna, Galdiero Massimiliano, Greco Rita, Finamore Emiliana
Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.
Department of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Naples, Italy.
Case Rep Infect Dis. 2025 Feb 6;2025:6452173. doi: 10.1155/crdi/6452173. eCollection 2025.
species constitute a diverse group of microorganisms classified as aerobic actinomyces. Among these species, many have been implicated as causative agents of severe human infections, particularly in immunocompromised patients, affecting lungs, skin, and nervous system. Here, we described a rare species, identified as isolated at the Complex Operative Unit of Virology and Microbiology from the subxiphoid formation and pseudonodular formation in the left leg of a 69-year-old immunocompetent patient, who was hospitalized and treated at the Complex Operative Unit of Internal Medicine and Geriatrics of the University Hospital of Campania "Luigi Vanvitelli" in an antimicrobial diagnostic stewardship context. This rare pathogen was first isolated in 2014 from a bronchoalveolar lavage sample obtained from a lung transplant recipient. Since then, only five cases of clinical interest have been described in literature.
该物种构成了一类分类为需氧放线菌的多样微生物群体。在这些物种中，许多已被认为是严重人类感染的病原体，特别是在免疫功能低下的患者中，会影响肺部、皮肤和神经系统。在此，我们描述了一种罕见物种，它是从一名69岁免疫功能正常的患者左腿剑突下肿物和假结节肿物中，在病毒学和微生物学综合手术单元分离得到的。该患者在坎帕尼亚大学医院“路易吉·万维泰利”内科和老年病学综合手术单元接受住院治疗，处于抗菌诊断管理背景下。这种罕见病原体于2014年首次从一名肺移植受者的支气管肺泡灌洗样本中分离出来。从那时起，文献中仅描述了5例具有临床意义的病例。
