Jiang Feng, Zhang Rong-Xin, Zhang Ya-Ping, Liu Zhen-Wei, Li Xuan, Wu Wei-Qun, Wen Bin, Deng Xin
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2016 Oct;36(10):1175-1179.
Objective To observe the features of syndrome patterns of Chinese medicine (CM) in elderly human immunodeficiency virus/acquired immune deficiency syndrome ( HIV/AIDS) patients in Guangxi Zhuang Autonomous Region. Methods According to a case-control study, a clinical question- naire was designated in elderly HIV/AIDS patients older than 50 years and healthy examinees with age and sex match. Their syndrome information of CM were collected from designated medical institutions in Guangxi Zhuang Autonomous Region from October 2013 to April 2014. Analyses of syndrome factors were conducted using WF-I[A Diagnosis and Treatment System of Traditional Chinese Medicine (Auxilia- ry). The disease location of CM and nature of diseases were compared between elderly HIV/AIDS patients and the controls. The features of syndrome patterns of CM in elderly HIV/AIDS patients were summarized. Results A total of 417 elderly HIV/AIDS patients and 362 examinees were enrolled. In elderly patients with HIV/AIDS, established syndrome factors of disease nature were qi deficiency, yang deficiency, yin deficiency, blood deficiency, dampness, and phlegm , and established syndrome factors of disease loca- tion included Shen, Fei, Pi, and Gan. There were statistical differences in established syndrome factors of disease location or nature between elderly patients with HIV/AIDS and the controls (P <0. 05). Conclu- sions Elderly HIV/AIDS patients were characterized by deficiency of qi, yang, yin, and blood in Shen, Fei, Pi, and Gan, as well as endogenous production of pathogenic factors such as dampness and phlegm. Intermingled deficiency and excess was dominated in elderly HIV/AIDS patients, and mainly man- ifested as deficiency syndrome.
目的 观察广西壮族自治区老年人类免疫缺陷病毒/获得性免疫缺陷综合征(HIV/AIDS)患者的中医证候特点。方法 采用病例对照研究方法,对50岁以上的老年HIV/AIDS患者及年龄、性别相匹配的健康体检者设计临床调查问卷。于2013年10月至2014年4月从广西壮族自治区指定医疗机构收集他们的中医证候信息。运用WF-I[A中医诊疗辅助系统]进行证候因素分析。比较老年HIV/AIDS患者与对照组的中医病位和病性。总结老年HIV/AIDS患者的中医证候特点。结果 共纳入417例老年HIV/AIDS患者和362例体检者。老年HIV/AIDS患者中,已确立的病性证候因素为气虚、阳虚、阴虚、血虚、湿、痰,已确立的病位证候因素包括肾、肺、脾、肝。老年HIV/AIDS患者与对照组在已确立的病位或病性证候因素方面存在统计学差异(P<0.05)。结论 老年HIV/AIDS患者以肾、肺、脾、肝的气、阳、阴、血亏虚,以及湿、痰等内生邪气为特征。老年HIV/AIDS患者以虚实夹杂为主,且以虚证为主。