Zhang Ying, Ma Jian-Ping, Ma Xiu-Lan, Abud-Ureyimu Aihemaiti, Li Jing-Ru, Zeng Li
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2016 Oct;36(10):1180-1183.
Objective To observe the correlation between the distribution of Chinese medicine (CM) syndromes and CD4 + T lymphocyte counts of acquired immune deficiency syndrome (AIDS) patients in Xin- jiang region. Methods Totally data (four diagnostic information of CM) of 787 HIV+ patients were collected and syndrome typed from 6 places with higher incidence of AIDS (Urumqi region, Aksu region, Turpan region, Yili region, Kashi region, and Bazhou region). CD4 + T lymphocyte counts were detected in AIDS patients with each syndrome. The correlations of CD4 + T lymphocyte counts and distributions of CM syndrome types were ana- lyzed. Results Qi-yin deficiency syndrome (QYDS) and qi deficiency and dampness resistance syndrome (QDDRS) were dominant in AIDS patients in Urumqi region and Aksu region. Gan stagnation qi stasis syn- drome (GSQSS) was more often seen in AIDS patients in Turpan region. QDDRS was more often seen in AIDS patients in Yili Region. Gan-Shen yin deficiency syndrome (GSYDS) was more often seen in AIDS patients in Kashi region. QYDS was more often seen in AIDS patients in Bazhou region. Fei-Shen yin deficiency syndrome (FSYDS) was more often seen in AIDS patients with CD4 T lymphocytes less than 200/μL. FSYDS and qi stag- nation phlegm coagulation syndrome (QSPCS) were more often seen in AIDS patients with CD4+ T lympho- cytes ranging 201 -350/μL. QDDRS and QYDS were more often seen in AIDS patients with CD4 + T lymphocytes ranging 351 -500/μL. Unconsolidated Fei-qi syndrome (UFQS) and Pi-qi deficiency syndrome (PQDS) were more often seen in AIDS patients with CD4+ T lymphocytes more than 501/μL (P <0. 05). Conclusions There existed different T-lymphocyte levels in AIDS patients with various syndrome types of CM in Xinjiang region, with certain correlation. Along with decreased CD4+T lymphocyte counts, AIDS patients' CM syndromes mani- fested a changing process from superficiality to interior syndrome, and from intermingled syndromes of defi- ciency and excess to deficiency syndrome.
目的 观察新疆地区获得性免疫缺陷综合征（AIDS）患者中医证候分布与CD4+T淋巴细胞计数的相关性。方法 收集乌鲁木齐地区、阿克苏地区、吐鲁番地区、伊犁地区、喀什地区、巴音郭楞蒙古自治州6个AIDS高发地区787例HIV阳性患者的资料（中医四诊信息）并进行辨证分型。检测各证型AIDS患者的CD4+T淋巴细胞计数，分析CD4+T淋巴细胞计数与中医证型分布的相关性。结果 乌鲁木齐地区和阿克苏地区AIDS患者以气阴两虚证和气虚夹湿证为主；吐鲁番地区AIDS患者肝郁气滞证多见；伊犁地区AIDS患者气虚夹湿证多见；喀什地区AIDS患者肝肾阴虚证多见；巴音郭楞蒙古自治州AIDS患者气阴两虚证多见。CD4+T淋巴细胞计数＜200/μL的AIDS患者肺肾阴虚证多见；CD4+T淋巴细胞计数在201～350/μL的AIDS患者肺肾阴虚证和气滞痰凝证多见；CD4+T淋巴细胞计数在351～500/μL的AIDS患者气虚夹湿证和气阴两虚证多见；CD4+T淋巴细胞计数＞501/μL的AIDS患者肺脾气虚证和脾气虚证多见（P＜0.０5）。结论 新疆地区不同中医证型的AIDS患者存在不同的T淋巴细胞水平，具有一定的相关性。随着CD4+T淋巴细胞计数的降低，AIDS患者的中医证候呈现由表入里、由虚实夹杂向虚证演变的过程。
