[辐射对不同放射敏感性组织中糖皮质激素细胞内受体的影响]
[Effect of irradiation on the intracellular reception of glucocorticoids in tissues with various radiosensitivities].
作者信息
Konoplia E F, Luksha G L, Gavrilin M A
出版信息
Radiobiologiia. 1988 Nov-Dec;28(6):772-4.
PMID:3064133
Abstract
The experiments with albino female rats showed that whole-body gamma-irradiation with a dose of 1 Gy caused various alterations in concentrations of cytoplasmic and nuclear glucocorticoid receptors depending on tissue radiosensitivity (liver, thymus) and postirradiation time-intervals (1, 3, 10, 30, and 60 days). There was also a change in the receptor affinity to glucocorticoids.
摘要
对白化雌性大鼠进行的实验表明，剂量为1 Gy的全身γ射线照射会导致细胞质和细胞核糖皮质激素受体浓度发生各种变化，这取决于组织的放射敏感性（肝脏、胸腺）以及照射后的时间间隔（1、3、10、30和60天）。糖皮质激素受体的亲和力也发生了变化。
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